Protein Alignment CG6465 and ABHD14A-ACY1

DIOPT Version :9

• Sequence 1: NP_650004.1
• Gene: CG6465 / 41274
• FlyBaseID: FBgn0037818
• Length: 401
• Species: Drosophila melanogaster
• Sequence 2: NP_001303260.1
• Gene: ABHD14A-ACY1 / 100526760
• HGNCID: 38856
• Length: 498
• Species: Homo sapiens
• Alignment Length: 407
• Identity: 203/407 - (49%)
• Similarity: 264/407 - (64%)
• Gaps: 15/407 - (3%)

  Fly     3 TSKWESDE--EIQYFREYLRIPSVHPDPDYAPCVEFLRRQANLMDLP-MKVYYPANEQNP---VV 61
            |||...:|  .:..||:||||.:|.|.|||...|.|....|..:.|. .||     |..|   |.
Human    92 TSKGPEEEHPSVTLFRQYLRIRTVQPKPDYGAAVAFFEETARQLGLGCQKV-----EVAPGYVVT 151

  Fly    62 VLTWKGLNPELPSILLNSHMDVVPVFPENWTHPPFGADIDEEGRIFARGTQDMKSVGMQHLAAVR 126
            ||||.|.||.|.|||||||.||||||.|:|:|.||.|..|.||.|:|||.||||.|.:|:|.|||
Human   152 VLTWPGTNPTLSSILLNSHTDVVPVFKEHWSHDPFEAFKDSEGYIYARGAQDMKCVSIQYLEAVR 216

  Fly   127 ALKRSGAKFKRTIHISFVADEEMGGRYGMRPFVPTEDFRALNVGFAMDEGLASPDEQLPLFYAER 191
            .||..|.:|.||||::||.|||:||..||..||...:|.||..|||:|||:|:|.:...:||:||
Human   217 RLKVEGHRFPRTIHMTFVPDEEVGGHQGMELFVQRPEFHALRAGFALDEGIANPTDAFTVFYSER 281

  Fly   192 AVWRVYFNISGTAGHGSLLLPNTAGEKLNYIVGKMMEFRRSQVQRLQNNPELVIGDVTTINLTKL 256
            :.|.|....:|..||.|..:.:||.|||:.:|..::.||..:.||||:||.|..|.||::|||||
Human   282 SPWWVRVTSTGRPGHASRFMEDTAAEKLHKVVNSILAFREKEWQRLQSNPHLKEGSVTSVNLTKL 346

  Fly   257 GGGVQSNVVPPLLMVCFDCRLALDVDFEEFEANLHKWCADVGGGIEITYEQK--QPKVPPTAIDG 319
            .|||..||:|..:...||.|:|.||||:.||..|..||...|.|:.:.:.||  .|:|.||  |.
Human   347 EGGVAYNVIPATMSASFDFRVAPDVDFKAFEEQLQSWCQAAGEGVTLEFAQKWMHPQVTPT--DD 409

  Fly   320 SNPFWLAFKKATDEMHISIKPQIFTGGTDSRYIRAVGIPALGFSPMNNTPVLLHDHDEFIQADIY 384
            |||:|.||.:...:|:::::|:|....||:|||||||:|||||||||.||||||||||.:...::
Human   410 SNPWWAAFSRVCKDMNLTLEPEIMPAATDNRYIRAVGVPALGFSPMNRTPVLLHDHDERLHEAVF 474

  Fly   385 LRGVQIFQKIISNIANV 401
            ||||.|:.:::..:|:|
Human   475 LRGVDIYTRLLPALASV 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6465	NP_650004.1	Ac-peptdase-euk	1..401	CDD:273850	202/405 (50%)
		M20_AcylaseI_like	8..399	CDD:193524	198/398 (50%)
ABHD14A-ACY1	NP_001303260.1	Ac-peptdase-euk	91..491	CDD:273850	202/405 (50%)
		M20_AcylaseI_like	99..489	CDD:193524	198/396 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148083
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1432382at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100626
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2059
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	6	5.730