Protein Alignment hth and CUP9

DIOPT Version :10

• Sequence 1: NP_476576.1
• Gene: hth / 41273
• FlyBaseID: FBgn0001235
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_015148.1
• Gene: CUP9 / 855926
• SGDID: S000006098
• Length: 306
• Species: Saccharomyces cerevisiae
• Alignment Length: 226
• Identity: 61/226 - (26%)
• Similarity: 95/226 - (42%)
• Gaps: 33/226 - (14%)

  Fly   201 PIDLVIDERDTTKPPELGSANGE-GRSNADSTSHTDGASTPDVRPPSSSLSYGGAMNDDARSPGA 264
            ||.::.:..:....|||..:|.| ...|..|::.......|.:.|...|::| .|:|....|..|
Yeast    23 PIQVLFNSIEKRSMPELAFSNIEYSHGNLRSSTEEQNYPAPVLLPQHHSIAY-PAINSGGTSTTA 86

  Fly   265 GSTPGPLSQQPPALDTSDPDGKFLSSLNPSELTYDGRWCRREWSSPADA---RNADASRRLYSSV 326
            ..|...:.....:....|...::.||......:.|.:.|.:  |:|...   :..||..: |:..
Yeast    87 TPTASTVETSKTSSSAMDTQSQYGSSKKSKSASDDAKPCYK--SAPIYEIINKEKDAGAQ-YNRP 148

  Fly   327 FLGSPDNFGTSASGDASNASIGSGEGTGEEDDDASGKKNQKKRGIFPKVATNILRAWLFQHLTHP 391
            |    .:|..|.|                     ..|:|..:|...||....||..||..||.:|
Yeast   149 F----SDFVESKS---------------------RRKQNSGRRSNLPKETVQILNTWLLNHLNNP 188

  Fly   392 YPSEDQKKQLAQDTGLTILQVNNWFINARRR 422
            ||::.:|::|...||||.:|::|||||.|||
Yeast   189 YPTQQEKRELLIKTGLTKIQLSNWFINVRRR 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hth	NP_476576.1	Meis_PKNOX_N	127..211	CDD:465140	2/9 (22%)
		Homeobox_KN	384..422	CDD:428673	19/37 (51%)
CUP9	NP_015148.1	Homeobox_KN	181..219	CDD:428673	19/37 (51%)