DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hth and BLH1

DIOPT Version :9

Sequence 1:	NP_476576.1	Gene:	hth / 41273	FlyBaseID:	FBgn0001235	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	NP_001031490.1	Gene:	BLH1 / 818167	AraportID:	AT2G35940	Length:	680	Species:	Arabidopsis thaliana

Alignment Length:	366	Identity:	84/366 - (22%)
Similarity:	130/366 - (35%)	Gaps:	129/366 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 KPPELGSANGEGR-----SNADSTSHTDG----------------------ASTPDVRPPSS--S 248
            :|..:|..:|.|.     |.:..:..|:|                      |.:.|:...|.  |
plant   158 QPIHVGFGSGHGEDIRVGSGSTGSGVTNGIANLVSSKYLKAAQELLDEVVNADSDDMNAKSQLFS 222

  Fly   249 LSYGGAMND------DARSPGAGSTPG--PLSQQPPALDTSDPDGKFLSSLNPSELTYDGRWCRR 305
            ...|...||      .|.:.|.||..|  ...::|..|.|::.....:.....|.:.::.....|
plant   223 SKKGSCGNDKPVGESSAGAGGEGSGGGAEAAGKRPVELGTAERQEIQMKKAKLSNMLHEVEQRYR 287

  Fly   306 EWS-------SPADARNADASRRLYSSVFLGSPDN----FGTSASGD--ASNASIGSGEGTGEED 357
            ::.       |..:......|.:.|:|:.|.:...    ...:.:|.  |:|.|:|       |:
plant   288 QYHQQMQMVISSFEQAAGIGSAKSYTSLALKTISRQFRCLKEAIAGQIKAANKSLG-------EE 345

  Fly   358 DDASG---------------KKNQK------------------KRGIFPKVATNILRAWLFQHLT 389
            |..||               .:.|:                  :||: |:.|.::||||||:|..
plant   346 DSVSGVGRFEGSRLKFVDHHLRQQRALQQLGMIQHPSNNAWRPQRGL-PERAVSVLRAWLFEHFL 409

  Fly   390 HPYPSEDQKKQLAQDTGLTILQVNNWFINARRRIVQPMI-----------------------DQS 431
            ||||.:..|..||:.||||..||:|||||||.|:.:||:                       |||
plant   410 HPYPKDSDKHMLAKQTGLTRSQVSNWFINARVRLWKPMVEEMYMEEMKEQAKNMGSMEKTPLDQS 474

  Fly   432 N-----RAVYTPHPGPSGYGHDAMGYMMDSQAHMMHRPPGD 467
            |     ::.......|          |.|:..||.....||
plant   475 NEDSASKSTSNQEKSP----------MADTNYHMNPNHNGD 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hth	NP_476576.1	Meis_PKNOX_N	127..211	CDD:406806
hth	NP_476576.1	Homeobox_KN	383..422	CDD:399131	24/38 (63%)
BLH1	NP_001031490.1	POX	190..332	CDD:400075	22/141 (16%)
BLH1	NP_001031490.1	Homeobox_KN	403..442	CDD:399131	24/38 (63%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	60	1.000	Domainoid score	I3843
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2647
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11850
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X78
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.000