Protein Alignment hth and pknox1.1

DIOPT Version :9

• Sequence 1: NP_476576.1
• Gene: hth / 41273
• FlyBaseID: FBgn0001235
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_571966.3
• Gene: pknox1.1 / 798151
• ZFINID: ZDB-GENE-020122-5
• Length: 433
• Species: Danio rerio
• Alignment Length: 392
• Identity: 147/392 - (37%)
• Similarity: 194/392 - (49%)
• Gaps: 110/392 - (28%)

  Fly    61 GYHSGAGGHGTPSHVSPVGNHLMGAIPEVHKR-DKDAIYEHPLFPLLALIFEKCELATCTPREPG 124
            |:.:|..|:.:    |||.|.     |:.... ||..||.|||||||||:|||||.:|.
Zfish    32 GFSNGNTGNTS----SPVSNE-----PQTQMDIDKACIYRHPLFPLLALLFEKCEQSTL------ 81

  Fly   125 VQGGDVCSSESFNEDIAMFSKQIRSQ----KPYYTADPEVDSLMVQAIQVLRFHLLELEKVHELC 185
              |.|..:|.||:.||..|   :|||    |.:::.||::|:|||:||||||.||||||||.:||
Zfish    82 --GSDCVTSASFDVDIENF---VRSQEKDGKAFFSEDPDLDNLMVKAIQVLRIHLLELEKVSDLC 141

  Fly   186 DNFCHRYISCLKGKMPIDLVIDERDTTKPPELGSANGEGRSNAD-----STSHTDGASTPDVRP- 244
            .:||.|||||||.||                    |.|...:.|     |..| |..|.|...|
Zfish   142 KDFCSRYISCLKAKM--------------------NSETLLSGDPGSPYSPVH-DQLSNPFSGPL 185

  Fly   245 -------PSSSLSYGGAMNDDARSPGAGSTPGPLSQQPPALDTSDPDGKFLS-SLNPSELTYDGR 301
                   |||.|..|........|....:  |....||..:.|  |.|:.:: :::|..|
Zfish   186 SPQSLLIPSSGLQQGSVTVTTVNSSQVAT--GNTVYQPVTVVT--PQGQVVTQAISPGAL----- 241

  Fly   302 WCRREWSSPADARNADASRRLYSSV-FLGSPDNFGTSASGDASNASIGSGEGTGEEDDDASGKKN 365
                      ..:|:....:|...: |.|.                           ||:|.|
Zfish   242 ----------HIQNSQLQLQLNQDLSFFGG---------------------------DDSSPK-- 267

  Fly   366 QKKRGIFPKVATNILRAWLFQHLTHPYPSEDQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQ 430
             .|||:.||.|||::|:|||||:.||||:|::|||:|..|.||:||||||||||||||:|||:|.
Zfish   268 -NKRGVLPKQATNVMRSWLFQHIAHPYPTEEEKKQIATQTNLTLLQVNNWFINARRRILQPMLDA 331

  Fly   431 SN 432
            ::
Zfish   332 NS 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hth	NP_476576.1	Meis_PKNOX_N	127..211	CDD:406806	45/87 (52%)
		Homeobox_KN	383..422	CDD:399131	28/38 (74%)
pknox1.1	NP_571966.3	Meis_PKNOX_N	82..166	CDD:293102	47/106 (44%)
		Homeobox_KN	284..323	CDD:283551	28/38 (74%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587121
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000410
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X78
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.740