Protein Alignment hth and Pknox2

DIOPT Version :9

• Sequence 1: NP_476576.1
• Gene: hth / 41273
• FlyBaseID: FBgn0001235
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_001258207.1
• Gene: Pknox2 / 680549
• RGDID: 1590611
• Length: 475
• Species: Rattus norvegicus
• Alignment Length: 455
• Identity: 162/455 - (35%)
• Similarity: 217/455 - (47%)
• Gaps: 127/455 - (27%)

  Fly    33 PPGLQGLPSHHSPHMT------------HAAAAAATVGMHGYHSGAGGHGTPSHVSPVGNHLMGA 85
            ||     |...||.||            |.||.:||.            .||...:|:.
  Rat    21 PP-----PYQDSPQMTATAQPPSKAQAVHIAAPSATA------------STPVPSAPID------ 62

  Fly    86 IPEVH-KRDKDAIYEHPLFPLLALIFEKCELATCTPREPGVQGGDVCSSESFNEDIAMF-SKQIR 148
             |:.. :.||.|:|.|||||||.|:|||||.||        ||.:..:|.||:.||..| .:|.:
  Rat    63 -PQAQLEADKRAVYRHPLFPLLTLLFEKCEQAT--------QGSECITSASFDVDIENFVHQQEQ 118

  Fly   149 SQKPYYTADPEVDSLMVQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDTTK 213
            ..||:::.|||:|:|||:||||||.||||||||:|||.:||:|||:|||.||..|.:: ..|...
  Rat   119 EHKPFFSDDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLL-RNDLGG 182

  Fly   214 P-----PELGSANGEGRSNADSTSHTDGASTPDVRPPSSSLSYGG----AMNDDARSPGAGSTPG 269
            |     |.:...:.:...|:.::......:...:..|:|:|..|.    .:|....|.||
  Rat   183 PYSPNQPSINLHSQDLLQNSPNSMSGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSGGA----- 242

  Fly   270 PLSQQPPALDTSDPDGKFLSSLNPSELTYDGRWCRREWSSPADARNADASRRLYSSVFLGSPDNF 334
              ..||..:.||  .|:.::...|              ......:|...:..|.|.:     ||
  Rat   243 --LYQPVTMVTS--QGQVVTQAIP--------------QGAIQIQNTQVNLDLTSLL-----DN- 283

  Fly   335 GTSASGDASNASIGSGEGTGEEDDDASGKKNQKKRGIFPKVATNILRAWLFQHLTHPYPSEDQKK 399
                                 ||     ||::.|||:.||.||||:|:||||||.||||:||:|:
  Rat   284 ---------------------ED-----KKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKR 322

  Fly   400 QLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVYTPHPGPSGYGHDAMGYMMDSQAHMMHRP 464
            |:|..|.||:||||||||||||||:|||:|.||     |.|.|..           .:....|||
  Rat   323 QIAAQTNLTLLQVNNWFINARRRILQPMLDASN-----PDPAPKA-----------KKIKSQHRP 371

  Fly   465  464
              Rat   372  371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hth	NP_476576.1	Meis_PKNOX_N	127..211	CDD:406806	45/84 (54%)
		Homeobox_KN	383..422	CDD:399131	29/38 (76%)
Pknox2	NP_001258207.1	gliding_GltG	5..>77	CDD:411344	20/79 (25%)
		Meis_PKNOX_N	96..181	CDD:406806	46/85 (54%)
		Homeobox_KN	306..345	CDD:399131	29/38 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346169
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000410
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X78
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.740