Protein Alignment hth and pbx1a

DIOPT Version :9

• Sequence 1: NP_476576.1
• Gene: hth / 41273
• FlyBaseID: FBgn0001235
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_571689.1
• Gene: pbx1a / 58138
• ZFINID: ZDB-GENE-000405-1
• Length: 428
• Species: Danio rerio
• Alignment Length: 451
• Identity: 91/451 - (20%)
• Similarity: 132/451 - (29%)
• Gaps: 196/451 - (43%)

  Fly     3 QPRYDDGLHGYGMDSGAAAAAMYDPHAGHRPPGLQGLPSHHSPHMTHAAAAAATVGMHGYHSGAG 67
            |||.....||.||             |||  |||       :.||               ..|.|
Zfish     4 QPRLMHSSHGVGM-------------AGH--PGL-------AQHM---------------QDGTG 31

  Fly    68 GHGTPSHVSPVGNHLM-------GAIPEVHKRDKDAIYEH----PLFPLLALIFEKCELAT--CT 119
            |.........:||.|.       .::.|...| |.|:..|    .||.:|..|.||..|:.  ..
Zfish    32 GADDEGRKQDIGNILQQIMTITDQSLDEAQAR-KHALNCHRMKPALFNVLCEIKEKTVLSIRGAQ 95

  Fly   120 PREP---------------GVQGGDVCSSESFNEDIAMFSKQIRSQKPYYTADPEVDSLMVQAIQ 169
            ..||               ||.|.:.....:.....|..:..:.|..     ..|......:..|
Zfish    96 EEEPPDAQLMRLDNMLLAEGVSGPEKGGGSAAAAAAAAAAGGVGSDN-----SAEHSDYRAKLSQ 155

  Fly   170 VLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDTTKPPELGSANGEGRSNADSTSHT 234
            :.:.:..||||..:.|:.|....::.|:          |:..|:|
Zfish   156 IRQIYHTELEKYEQACNEFTTHVMNLLR----------EQSRTRP-------------------- 190

  Fly   235 DGASTPDVRPPSSSLSYGGAMNDDARSPGAGSTPGPLSQQPPALDTSDPDGKFLSSLNPSELTYD 299
                                                                    ::|.|:...
Zfish   191 --------------------------------------------------------ISPKEIERM 199

  Fly   300 GRWCRREWSS---PADARNADASRRLYSSVFLGSPDNFGTSASGDASNASIGSGEGTGEEDDDAS 361
            .....|::||   .......:|...|.|. ||                              ||
Zfish   200 VSIIHRKFSSIQMQLKQSTCEAVMILRSR-FL------------------------------DA- 232

  Fly   362 GKKNQKKRGIFPKVATNILRAWLFQHLTHPYPSEDQKKQLAQDTGLTILQVNNWFINARRR 422
                ::||..|.|.||.||..:.:.||::|||||:.|::||:...:|:.||:|||.|.|.|
Zfish   233 ----RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIR 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hth	NP_476576.1	Meis_PKNOX_N	127..211	CDD:406806	13/83 (16%)
		Homeobox_KN	383..422	CDD:399131	18/38 (47%)
pbx1a	NP_571689.1	PBC	39..231	CDD:281746	44/314 (14%)
		homeodomain	233..293	CDD:238039	27/57 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587127
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X78
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840