DRSC/TRiP Functional Genomics Resources

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Protein Alignment hth and irx1a

DIOPT Version :9

Sequence 1:NP_476576.1 Gene:hth / 41273 FlyBaseID:FBgn0001235 Length:487 Species:Drosophila melanogaster
Sequence 2:NP_997067.1 Gene:irx1a / 403019 ZFINID:ZDB-GENE-040707-1 Length:426 Species:Danio rerio


Alignment Length:229 Identity:51/229 - (22%)
Similarity:76/229 - (33%) Gaps:80/229 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   215 PELGSANGEGRSNADSTSHTDGASTPDVRPPSSSLS----------------YGGAMNDDARSPG 263
            |:||.......|.|.......|..||..|..|:.:.                |..|.|..|..|.
Zfish     4 PQLGYPQYLSASQAVYGGDRPGVLTPSSRAGSAEIGGSASAAAAAMSSVLGMYPYAHNYSAFLPY 68

  Fly   264 AGSTPGPLSQQPPALDTSDPDG----KFLSSLNPSELTYDGRWCRREWSSPADARNADASRRLYS 324
            ..:.....||.....|..|..|    .|.:..:|:...| |::   ::..||..:||        
Zfish    69 TSADLALFSQMGSQYDLKDSPGVHPASFAAHTSPAFYPY-GQF---QYGDPARPKNA-------- 121

  Fly   325 SVFLGSPDNFGTSASGDASNASIGSGEGTGEEDDDASGKKNQKKRGIFPKVATNILRAWLFQHLT 389
                                                            .:.:|:.|:|||.:|..
Zfish   122 ------------------------------------------------TRESTSTLKAWLNEHRK 138

  Fly   390 HPYPSEDQKKQLAQDTGLTILQVNNWFINARRRI 423
            :|||::.:|..||..|.:|:.||:.||.|||||:
Zfish   139 NPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 172

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hthNP_476576.1 Meis_PKNOX_N 127..211 CDD:406806
Homeobox_KN 383..422 CDD:399131 18/38 (47%)
irx1aNP_997067.1 Homeobox_KN 132..171 CDD:283551 18/38 (47%)
IRO <276..289 CDD:214716
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.000

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