DRSC/TRiP Functional Genomics Resources

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Protein Alignment hth and irx4a

DIOPT Version :9

Sequence 1:NP_476576.1 Gene:hth / 41273 FlyBaseID:FBgn0001235 Length:487 Species:Drosophila melanogaster
Sequence 2:XP_021322341.1 Gene:irx4a / 402999 ZFINID:ZDB-GENE-040426-1825 Length:441 Species:Danio rerio


Alignment Length:232 Identity:59/232 - (25%)
Similarity:86/232 - (37%) Gaps:74/232 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   270 PLSQQPPALDTSD-------------PDGKFLSSLNPSEL-TYDGR---WCRREWSSPADARNAD 317
            |.|..|..|.|::             ||.   |:..|... .|:.|   ..|.|.||.       
Zfish     9 PYSSAPQFLMTTNSLTSCCESSTRSIPDS---SAQTPVYCPVYESRLLATARHELSSA------- 63

  Fly   318 ASRRLYSSVFLGSPD-----NFGTSASG-------DASNASIGSGEG-------------TGEED 357
            |:..:|.|.:.|...     .:|..||.       ||.:.|..:..|             .|:..
Zfish    64 AALGVYGSPYTGGQGYGNYVTYGADASAFYSLGTFDAKDGSASAHAGITPAAAYYPYDPTLGQYQ 128

  Fly   358 DDASG-------KKNQKKRGIFPKVATNILRAWLFQHLTHPYPSEDQKKQLAQDTGLTILQVNNW 415
            .|..|       :||..:.      .|:.|:|||.:|..:|||::.:|..||..|.:|:.||:.|
Zfish   129 YDRYGSMEGGTRRKNATRE------TTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTW 187

  Fly   416 FINARRRIVQPMIDQSNRAVYTPHPGPSGYGHDAMGY 452
            |.|||||     :.:.|:..:.|.    ..|.|...|
Zfish   188 FANARRR-----LKKENKMTWPPR----NKGSDEKKY 215

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hthNP_476576.1 Meis_PKNOX_N 127..211 CDD:406806
Homeobox_KN 383..422 CDD:399131 18/38 (47%)
irx4aXP_021322341.1 Abdominal-A <140..245 CDD:332641 30/91 (33%)
Homeobox_KN 155..194 CDD:310480 18/38 (47%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0773
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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