DRSC/TRiP Functional Genomics Resources

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Protein Alignment hth and irx2a

DIOPT Version :9

Sequence 1:NP_476576.1 Gene:hth / 41273 FlyBaseID:FBgn0001235 Length:487 Species:Drosophila melanogaster
Sequence 2:NP_957351.1 Gene:irx2a / 394032 ZFINID:ZDB-GENE-040426-1446 Length:432 Species:Danio rerio


Alignment Length:205 Identity:61/205 - (29%)
Similarity:88/205 - (42%) Gaps:51/205 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   243 RPPSSSLSYGGAM-----NDDAR-SPGAGSTPGPLSQQPPALDTSDPDGKFLSSLN--PSELTYD 299
            :||.|...|...:     .|.|| |.|:..:|.|.|            ..|.:|.|  .|.|.|.
Zfish    10 QPPGSLALYSCPLAAPRSEDLARSSSGSAFSPYPGS------------AAFTASANGFSSPLPYS 62

  Fly   300 GRWCRREWSSPADARNADASRRLYSSVFLGSP-DNFGTSASGDASNASIGSGEGTGEEDDDASGK 363
                    :.||..         :.| ::||| |...|..:|..|....|| .|...:.:|.:.:
Zfish    63 --------TDPATG---------FPS-YMGSPYDAHTTGMAGAISYHPYGS-PGYPYQLNDPAYR 108

  Fly   364 KNQKKRGIFPKVATNILRAWLFQHLTHPYPSEDQKKQLAQDTGLTILQVNNWFINARRRIVQPMI 428
            ||..:.      ||..|:|||.:|..:|||::.||..||..|.:|:.||:.||.|||||     :
Zfish   109 KNATRD------ATATLKAWLQEHRKNPYPTKGQKIMLAIITKMTLTQVSTWFANARRR-----L 162

  Fly   429 DQSNRAVYTP 438
            .:.|:..:.|
Zfish   163 KKENKMTWAP 172

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hthNP_476576.1 Meis_PKNOX_N 127..211 CDD:406806
Homeobox_KN 383..422 CDD:399131 19/38 (50%)
irx2aNP_957351.1 Homeobox_KN 122..161 CDD:283551 19/38 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0773
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.900

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