Protein Alignment hth and exd

DIOPT Version :9

• Sequence 1: NP_476576.1
• Gene: hth / 41273
• FlyBaseID: FBgn0001235
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_001259592.1
• Gene: exd / 32567
• FlyBaseID: FBgn0000611
• Length: 376
• Species: Drosophila melanogaster
• Alignment Length: 429
• Identity: 94/429 - (21%)
• Similarity: 151/429 - (35%)
• Gaps: 149/429 - (34%)

  Fly   120 PREPGVQG---GDVCSSESFNEDIAMFSKQIRSQKPYYTADPEVDSLMVQAIQVLRFHLLELE-K 180
            |:..|:.|   |....||:          ::|.||       ::..::.|.:.:....|.|.: :
  Fly    17 PQGYGLSGQDDGQNAGSEN----------EVRKQK-------DIGEILQQIMSISEQSLDEAQAR 64

  Fly   181 VHELCDNFCHRY------ISC-LKGKMPIDLVIDERDTTKPPELGSANGEGRSNADSTSHTDGAS 238
            .|.|   .|||.      :.| :|.|..:.:...:.:....|:|        ...|:....:|.:
  Fly    65 KHTL---NCHRMKPALFSVLCEIKEKTVLSIRNTQEEEPPDPQL--------MRLDNMLIAEGVA 118

  Fly   239 TPDVRPPSSSLSYGGAMNDDARSPGAGSTPGPLS--QQPPALDTSDPDGKF--LSSLNPSELTYD 299
            .|:       ...|||.   |.|..|.|..|.||  ....|::.||...|.  :..:...||...
  Fly   119 GPE-------KGGGGAA---AASAAAASQGGSLSIDGADNAIEHSDYRAKLAQIRQIYHQELEKY 173

  Fly   300 GRWCR----------REWS-----SPAD-ARNADASRRLYSSV------------------FLGS 330
            .:.|.          ||.|     :|.: .|......:.:||:                  ||
  Fly   174 EQACNEFTTHVMNLLREQSRTRPITPKEIERMVQIIHKKFSSIQMQLKQSTCEAVMILRSRFL-- 236

  Fly   331 PDNFGTSASGDASNASIGSGEGTGEEDDDASGKKNQKKRGIFPKVATNILRAWLFQHLTHPYPSE 395
                                        ||     ::||..|.|.|:.||..:.:.||::|||||
  Fly   237 ----------------------------DA-----RRKRRNFSKQASEILNEYFYSHLSNPYPSE 268

  Fly   396 DQKKQLAQDTGLTILQVNNWFINAR---RRIVQPMIDQSNRAVYTPHPGPSGYG----------- 446
            :.|::||:..|:|:.||:|||.|.|   ::.:....:::|........|.|.|.
  Fly   269 EAKEELARKCGITVSQVSNWFGNKRIRYKKNIGKAQEEANLYAAKKAAGASPYSMAGPPSGTTTP 333

  Fly   447 -------HDAMGYMMDSQAHMMHRPPG------DPGFHQ 472
                   .|:|||.|.|..:...:|..      ||..||
  Fly   334 MMSPAPPQDSMGYPMGSGGYDQQQPYDNSMGGYDPNLHQ 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hth	NP_476576.1	Meis_PKNOX_N	127..211	CDD:406806	18/94 (19%)
		Homeobox_KN	383..422	CDD:399131	19/41 (46%)
exd	NP_001259592.1	PBC	41..237	CDD:397732	43/253 (17%)
		homeodomain	239..299	CDD:238039	26/59 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457276
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11850
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X78
	4	3.940