DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hth and tgif1

DIOPT Version :9

Sequence 1:	NP_476576.1	Gene:	hth / 41273	FlyBaseID:	FBgn0001235	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	NP_955861.1	Gene:	tgif1 / 321756	ZFINID:	ZDB-GENE-030131-475	Length:	273	Species:	Danio rerio

Alignment Length:	170	Identity:	55/170 - (32%)
Similarity:	69/170 - (40%)	Gaps:	62/170 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   349 SGEGTGEEDD-----------DASGKKNQKKRGIFPKVATNILRAWLFQHLTHPYPSEDQKKQLA 402
            ||..|.:||.           ..|||:  |:||..||.:..|||.||:||..:.||||.:|..|:
Zfish    11 SGSETEDEDSLDVPLDLSSNGGVSGKR--KRRGNLPKESVQILRDWLYQHRYNAYPSEQEKALLS 73

  Fly   403 QDTGLTILQVNNWFINARRRIVQPMI------------------------DQSNRAVYTPHPGPS 443
            :.|.|:.|||.|||||||||::..|:                        |.|.    :|..|..
Zfish    74 KQTHLSTLQVCNWFINARRRLLPEMLRKDGKDPNQFTISRRGSKGGEMLSDNSQ----SPKHGLL 134

  Fly   444 GYGHDAMGYMMDSQAHMMHRPPGDPGFH--------QGYP 475
            ..|.|...|           .||.|  |        .|||
Zfish   135 ANGEDRNSY-----------EPGSP--HPTSNTPTSNGYP 161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hth	NP_476576.1	Meis_PKNOX_N	127..211	CDD:406806
hth	NP_476576.1	Homeobox_KN	383..422	CDD:399131	22/38 (58%)
tgif1	NP_955861.1	Homeobox_KN	54..93	CDD:283551	22/38 (58%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587118
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740