DRSC/TRiP Functional Genomics Resources

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Protein Alignment hth and Pbx3

DIOPT Version :9

Sequence 1:NP_476576.1 Gene:hth / 41273 FlyBaseID:FBgn0001235 Length:487 Species:Drosophila melanogaster
Sequence 2:NP_001101304.1 Gene:Pbx3 / 311876 RGDID:1307198 Length:434 Species:Rattus norvegicus


Alignment Length:499 Identity:86/499 - (17%)
Similarity:133/499 - (26%) Gaps:258/499 - (51%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 AGHRPPGLQGLPSHHSPHMTHAAAAAATVGMHGYHSGAGGHGTPSHVSPVGNHLM----GAIPEV 89
            |||...|...||.  .||               .|.||.|.|....:..:.:.:|    .::.|.
  Rat    17 AGHSVQGGMALPP--PPH---------------GHEGADGDGRKQDIGDILHQIMTITDQSLDEA 64

  Fly    90 HKRDKDAIYEHPLFPLLALIFEKCELATCT-----------PREP------------GVQGGD-- 129
            ..: |.|:..|.:.|  ||....||:...|           |.:|            ||.|.:  
  Rat    65 QAK-KHALNCHRMKP--ALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGVSGPEKG 126

  Fly   130 ----------VCSSESFNEDIAMFSKQIRSQKPYYTADPEVDSLMVQAIQVLRFHLLELEKVHEL 184
                      ..|..|.:..|                  |......:..|:.:.:..||||..:.
  Rat   127 GGSAAAAAAAAASGGSSDNSI------------------EHSDYRAKLTQIRQIYHTELEKYEQA 173

  Fly   185 CDNFCHRYISCLKGKMPIDLVIDERDTTKPPELGSANGEGRSNADSTSHTDGASTPDVRPPSSSL 249
            |:.|....::.|:          |:..|:|                                   
  Rat   174 CNEFTTHVMNLLR----------EQSRTRP----------------------------------- 193

  Fly   250 SYGGAMNDDARSPGAGSTPGPLSQQPPALDTSDPDGKFLSSLNPSELTYDGRWCRREWSSPADAR 314
                                                     ::|.|:                .|
  Rat   194 -----------------------------------------ISPKEI----------------ER 201

  Fly   315 NADASRRLYSSV------------------FLGSPDNFGTSASGDASNASIGSGEGTGEEDDDAS 361
            ......|.:||:                  ||                              || 
  Rat   202 MVGIIHRKFSSIQMQLKQSTCEAVMILRSRFL------------------------------DA- 235

  Fly   362 GKKNQKKRGIFPKVATNILRAWLFQHLTHPYPSEDQKKQLAQDTGLTILQVNNWFINARRR---- 422
                ::||..|.|.||.||..:.:.||::|||||:.|::||:...:|:.||:|||.|.|.|    
  Rat   236 ----RRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKN 296

  Fly   423 ----------------------IVQPMIDQSNRAVYTPHPGPSG 444
                                  :...:.:....:..||:.|.||
  Rat   297 IGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGSSG 340

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hthNP_476576.1 Meis_PKNOX_N 127..211 CDD:406806 14/95 (15%)
Homeobox_KN 383..422 CDD:399131 18/38 (47%)
Pbx3NP_001101304.1 PBC 43..234 CDD:397732 39/343 (11%)
homeodomain 236..296 CDD:238039 27/59 (46%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166346167
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X78
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.840

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