Protein Alignment hth and Pbx1

DIOPT Version :9

• Sequence 1: NP_476576.1
• Gene: hth / 41273
• FlyBaseID: FBgn0001235
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: XP_006496762.1
• Gene: Pbx1 / 18514
• MGIID: 97495
• Length: 450
• Species: Mus musculus
• Alignment Length: 434
• Identity: 83/434 - (19%)
• Similarity: 126/434 - (29%)
• Gaps: 204/434 - (47%)

  Fly    45 PHMTHAAAAAATVGMHGY-------HSGAGG-HGTPSHVSPVGNHLM-------GAIPEVHKRDK 94
            |.:.|:.|.   |||.|:       ..|||| .|.......:|:.|.       .::.|...| |
Mouse     5 PRLMHSHAG---VGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDEAQAR-K 65

  Fly    95 DAIYEHPLFPLLALIFEKCELATCT-----------PREP------------GVQGGDVCSSESF 136
            .|:..|.:.|  ||....||:...|           |.:|            ||.|.:.....:.
Mouse    66 HALNCHRMKP--ALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGPEKGGGSAA 128

  Fly   137 NEDIAMFSKQIRSQKPYYTADPEVDSLMVQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMP 201
            ....|..|....|......:|     ...:..|:.:.:..||||..:.|:.|....::.|:
Mouse   129 AAAAAAASGGAGSDNSVEHSD-----YRAKLSQIRQIYHTELEKYEQACNEFTTHVMNLLR---- 184

  Fly   202 IDLVIDERDTTKPPELGSANGEGRSNADSTSHTDGASTPDVRPPSSSLSYGGAMNDDARSPGAGS 266
                  |:..|:|
Mouse   185 ------EQSRTRP---------------------------------------------------- 191

  Fly   267 TPGPLSQQPPALDTSDPDGKFLSSLNPSELTYDGRWCRREWSSPADARNADASRRLYSSV----- 326
                                    ::|.|:                .|......|.:||:
Mouse   192 ------------------------ISPKEI----------------ERMVSIIHRKFSSIQMQLK 216

  Fly   327 -------------FLGSPDNFGTSASGDASNASIGSGEGTGEEDDDASGKKNQKKRGIFPKVATN 378
                         ||                              ||     ::||..|.|.||.
Mouse   217 QSTCEAVMILRSRFL------------------------------DA-----RRKRRNFNKQATE 246

  Fly   379 ILRAWLFQHLTHPYPSEDQKKQLAQDTGLTILQVNNWFINARRR 422
            ||..:.:.||::|||||:.|::||:..|:|:.||:|||.|.|.|
Mouse   247 ILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hth	NP_476576.1	Meis_PKNOX_N	127..211	CDD:406806	14/83 (17%)
		Homeobox_KN	383..422	CDD:399131	19/38 (50%)
Pbx1	XP_006496762.1	PBC	40..232	CDD:367661	41/331 (12%)
		homeodomain	234..294	CDD:238039	28/57 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842701
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X78
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840