DRSC/TRiP Functional Genomics Resources

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Protein Alignment hth and pknox1.2

DIOPT Version :9

Sequence 1:NP_476576.1 Gene:hth / 41273 FlyBaseID:FBgn0001235 Length:487 Species:Drosophila melanogaster
Sequence 2:XP_005171069.1 Gene:pknox1.2 / 170445 ZFINID:ZDB-GENE-020123-1 Length:445 Species:Danio rerio


Alignment Length:357 Identity:127/357 - (35%)
Similarity:177/357 - (49%) Gaps:98/357 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    94 KDAIYEHPLFPLLALIFEKCELATCTPREPGVQGGDVCSSESFNEDIAMFSK-QIRSQKPYYTAD 157
            |.|||.|||||||||:|||||.:|        |..:..:|.||:.||..|.: |.:..|.:::.|
Zfish    66 KSAIYRHPLFPLLALLFEKCEQST--------QSSECVTSASFDVDIENFVRNQEKEGKAFFSED 122

  Fly   158 PEVDSLMVQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDTTKPPELGSANG 222
            |::|:|||:||||||.||||||||::||.:||.|||:|||.||                    |.
Zfish   123 PDLDNLMVKAIQVLRIHLLELEKVNDLCKDFCSRYIACLKTKM--------------------NS 167

  Fly   223 EGRSNADSTSHTDGASTPDVRPPSSSLSYGGAMNDDARSPGAGSTPGPLSQQPPALDTSDPDG-- 285
            |...:.|                                ||:..:|.|...|.|......|.|  
Zfish   168 ETLLSGD--------------------------------PGSPYSPSPTQPQNPFTGAMSPQGIV 200

  Fly   286 ----------KFLSSLNPSELTYDGRWCRREWSSPADARNADASRRLYSSVFLGSPDNFGTSASG 340
                      ..::::||:::...|                    .:|..|.:.:|.....:.:.
Zfish   201 VPASALQQGNVTVTAVNPTQMVTGG--------------------TVYQPVTVVTPQGQVVTQTL 245

  Fly   341 DASNASIGSGEGTGEEDDDAS-----GKKNQKKRGIFPKVATNILRAWLFQHLTHPYPSEDQKKQ 400
            ......|.:.:...:.:.|.|     ...::.||||.||.|||::|:|||||:.||||:||:|||
Zfish   246 SPGTVRIQNSQLQLQLNQDLSFFSQEDGSSKAKRGILPKHATNVMRSWLFQHIGHPYPTEDEKKQ 310

  Fly   401 LAQDTGLTILQVNNWFINARRRIVQPMIDQSN 432
            :|..|.||:||||||||||||||:|||:|.|:
Zfish   311 IALQTNLTLLQVNNWFINARRRILQPMLDASS 342

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hthNP_476576.1 Meis_PKNOX_N 127..211 CDD:406806 40/84 (48%)
Homeobox_KN 383..422 CDD:399131 29/38 (76%)
pknox1.2XP_005171069.1 Meis_PKNOX_N 91..175 CDD:293102 43/135 (32%)
Homeobox_KN 293..332 CDD:283551 29/38 (76%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170587122
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0773
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000410
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X78
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
54.740

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