Protein Alignment hth and LOC1275836

DIOPT Version :10

• Sequence 1: NP_476576.1
• Gene: hth / 41273
• FlyBaseID: FBgn0001235
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: XP_061498620.1
• Gene: LOC1275836 / 1275836
• VectorBaseID: AGAMI1_002347
• Length: 821
• Species: Anopheles gambiae
• Alignment Length: 329
• Identity: 81/329 - (24%)
• Similarity: 113/329 - (34%)
• Gaps: 99/329 - (30%)

  Fly   218 GSANGEGRSNADSTSHTDGASTPDVRPPSSSLSYGGAMNDDAR------------SPGAGSTPGP 270
            |...|.|.....:||..:. ..|.:..|.|..:......|.||            |.|...||.|
Mosquito    96 GGGGGGGGGGGPTTSCCEN-GRPIMTDPVSGQTVCSCQYDSARLALSGYSRIPTGSVGVYGTPYP 159

  Fly   271 LSQQPPALDTSDPDGKFLSSL-NPSELTYDGRWCRREWSSPADARNADASRRLYSSVFLGSPDNF 334
            .::|.|..........|.|.| ||..|...|         |.....|..|..|..:
Mosquito   160 STEQNPYPSIGVDSSAFYSPLSNPYALKDSG---------PTSDMTAWTSAGLQPT--------- 206

  Fly   335 GTSASG----DASNASIGSGEGTGEEDDDASGKKNQKKRGIFPKVATNILRAWLFQHLTHPYPSE 395
                :|    |.:.|:.|.|.|.    |.|:.:||..:.      :|..|:|||.:|..:|||::
Mosquito   207 ----TGYYPYDPTLAAYGYGAGY----DLAARRKNATRE------STATLKAWLNEHKKNPYPTK 257

  Fly   396 DQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVYTP---------------------- 438
            .:|..||..|.:|:.||:.||.|||||     :.:.|:..:.|
Mosquito   258 GEKIMLAIITKMTLTQVSTWFANARRR-----LKKENKMTWEPKNKTDDDDDAMVSDDEKDKDDL 317

  Fly   439 HPGPSGYGHDAMGYMMDSQAHMM---------------HRPP----GDPGFHQG--YPHYPPAEY 482
            .|...|..|..|.:....|.|:.               .|.|    |.|| |.|  :|:|..:..
Mosquito   318 DPDKGGRDHKDMHHHHHHQHHVKSEHDKDEDDDDLTDDERKPENLMGHPG-HLGQHHPYYHHSML 381

  Fly   483 YGQH 486
            .|.|
Mosquito   382 GGHH 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hth	NP_476576.1	Meis_PKNOX_N	127..211	CDD:465140
		Homeobox_KN	384..422	CDD:428673	17/37 (46%)
LOC1275836	XP_061498620.1	None