DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment hth and irx1b

DIOPT Version :9

Sequence 1:NP_476576.1 Gene:hth / 41273 FlyBaseID:FBgn0001235 Length:487 Species:Drosophila melanogaster
Sequence 2:NP_571898.1 Gene:irx1b / 114430 ZFINID:ZDB-GENE-010716-1 Length:445 Species:Danio rerio


Alignment Length:245 Identity:60/245 - (24%)
Similarity:92/245 - (37%) Gaps:66/245 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   249 LSYGGAMNDDARSPGAGSTPG--PLSQQPPALDTSDPDGKFLSSLNPSELTYDGRWCRREWSSPA 311
            |.|...:|......||..| |  |.|.:..:.|.|.......:::.|....|...|..:.:|:..
Zfish     6 LGYPQFLNASQEVYGAERT-GVMPSSPREGSSDNSANPATAAAAITPMLGMYANPWTVQNYSAFL 69

  Fly   312 DARNADASRRLYSSVFLGS----PDNFGTSASGDASNASIG-SGEGTGEEDDDASGKKNQKKRGI 371
            ...:|:.:  |.|.  :||    .||.|....|.|.:|:.| ...|..:..|.|..|...::   
Zfish    70 PYNSAELA--LLSQ--MGSQYELKDNPGAHPPGFAVHAAPGFYPYGQYQYGDPARAKSATRE--- 127

  Fly   372 FPKVATNILRAWLFQHLTHPYPSEDQKKQLAQDTGLTILQVNNWFINARRRI------------- 423
                .|:.|:|||.:|..:|||::.:|..||..|.:|:.||:.||.|||||:             
Zfish   128 ----TTSTLKAWLQEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTCCRSAE 188

  Fly   424 ----------------------------------VQPMIDQSNRAVYTPH 439
                                              .:|.:||:..|...||
Zfish   189 DRDGRIFDSDNEDDADKNDDEEEIDLETIDMDKAEEPRVDQNKEAANNPH 238

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hthNP_476576.1 Meis_PKNOX_N 127..211 CDD:406806
Homeobox_KN 383..422 CDD:399131 18/38 (47%)
irx1bNP_571898.1 COG5576 <114..206 CDD:227863 26/98 (27%)
Homeobox_KN 135..174 CDD:283551 18/38 (47%)
IRO 287..304 CDD:214716
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0773
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.