DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hth and LOC100535338

DIOPT Version :9

Sequence 1:	NP_476576.1	Gene:	hth / 41273	FlyBaseID:	FBgn0001235	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	XP_005168761.1	Gene:	LOC100535338 / 100535338	-ID:	-	Length:	377	Species:	Danio rerio

Alignment Length:	158	Identity:	43/158 - (27%)
Similarity:	69/158 - (43%)	Gaps:	47/158 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   306 EWSSPADARNADASRRLYSSVFLGSPDNFGTSASGDASNASIGSGEGTGEEDDDASGKKNQKKRG 370
            |:|:.:|:...:.|.        |.|.|..||.....|:|                   .:::||
Zfish    17 EFSAMSDSDPCEDSD--------GFPLNLSTSGRRSGSSA-------------------KRRRRG 54

  Fly   371 IFPKVATNILRAWLFQHLTHPYPSEDQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNR-- 433
            ..||.:..:||.||::|..:.||||.:|..|:..|.|::.|:.|||||||||::..::.:..:
Zfish    55 NLPKESVQVLRDWLYEHRFNAYPSEQEKLSLSGQTHLSVSQICNWFINARRRLLPDLLRKDGKDP 119

  Fly   434 ------------------AVYTPHPGPS 443
                              ..:||.|.||
Zfish   120 TQFTMSRRTSKPDRSASPECHTPLPRPS 147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hth	NP_476576.1	Meis_PKNOX_N	127..211	CDD:406806
hth	NP_476576.1	Homeobox_KN	383..422	CDD:399131	19/38 (50%)
LOC100535338	XP_005168761.1	Homeobox_KN	67..103	CDD:283551	16/35 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587116
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840