DRSC/TRiP Functional Genomics Resources

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Protein Alignment hth and TGIF2-RAB5IF

DIOPT Version :9

Sequence 1:NP_476576.1 Gene:hth / 41273 FlyBaseID:FBgn0001235 Length:487 Species:Drosophila melanogaster
Sequence 2:NP_001186464.1 Gene:TGIF2-RAB5IF / 100527943 HGNCID:44664 Length:155 Species:Homo sapiens


Alignment Length:87 Identity:32/87 - (36%)
Similarity:47/87 - (54%) Gaps:15/87 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   343 SNASIGSGEGTGEEDDDASGKKNQKKRGIFPKVATNILRAWLFQHLTHPYPSEDQKKQLAQDTGL 407
            |::.:|..||.    ...:||:  |:||..||.:..|||.||:.|..:.||||.:|..|:..|.|
Human     2 SDSDLGEDEGL----LSLAGKR--KRRGNLPKESVKILRDWLYLHRYNAYPSEQEKLSLSGQTNL 60

  Fly   408 TILQ-----VNNWFINARRRIV 424
            ::||     |..||    |:|:
Human    61 SVLQDEFLDVIYWF----RQII 78

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hthNP_476576.1 Meis_PKNOX_N 127..211 CDD:406806
Homeobox_KN 383..422 CDD:399131 16/43 (37%)
TGIF2-RAB5IFNP_001186464.1 Homeobox_KN 36..>64 CDD:283551 11/27 (41%)
Rab5ip 70..146 CDD:284445 5/13 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0773
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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