DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp12e1 and CYP71A12

DIOPT Version :9

Sequence 1:	NP_650003.4	Gene:	Cyp12e1 / 41272	FlyBaseID:	FBgn0037817	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_180633.3	Gene:	CYP71A12 / 817626	AraportID:	AT2G30750	Length:	497	Species:	Arabidopsis thaliana

Alignment Length:	510	Identity:	124/510 - (24%)
Similarity:	211/510 - (41%)	Gaps:	102/510 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 IYQLCRGLAQKATAVNLEEAKPYADIPGPSKLQLIRAFLPGGLYK-NLPVHEMFLDMNRQYGSIF 79
            ::.|.:.|.:.|..|||.        |.|.:|.||     |.|:: :|..|.....::.:||.:.
plant    17 LFLLKQFLKRTANKVNLP--------PSPWRLPLI-----GNLHQLSLHPHRSLHSLSLRYGPLM 68

  Fly    80 -----RMPSVAGTDLVLTMNPQDYEVIFRNEGQYPYR-RSFEVMDYFKRVH------RREVFDGY 132
                 |:|.     ||::......||:..::.::..| ||       |.||      |..||..|
plant    69 LLHFGRVPI-----LVVSSGEAAQEVLKTHDLKFANRPRS-------KAVHGLMNGGRDVVFGPY 121

  Fly   133 DGLTSGNGPAWGKMRTAVNPILLQPRNAKLYMTNLVQVS------DEFLERIRIIRDPVTQEMPD 191
                   |..|.:|::.....||         ||.:..|      :|..|.|:.:....:....:
plant   122 -------GEYWRQMKSVCILNLL---------TNKMVASFEKIREEELNEMIKKLEKASSSSSSE 170

  Fly   192 DFAVDIRHLVIESICSVAL-NTHLGLLGEQRNNKDIQKLVLALQDVVELG-FQL-DIMPAFWKYL 253
            :.:.....|..:....:|| ..|    .|....:|::|.|..:.::  || |.: |.:||. .::
plant   171 NLSELFVTLPSDVTSRIALGRKH----SEDETARDLKKRVRQIMEL--LGEFPIGDYVPAL-AWI 228

  Fly   254 PMPN-----FKKLMRSLDTITDFCYFHIGNALKRIEEDAKAGTLNE------IGLETSLLEKLAR 307
            ...|     .|::.:....:.|          |.::|..:||...|      :.:|:   ||...
plant   229 DRINGFNARIKEVSQGFSDLMD----------KVVQEHLEAGNHKEDFVDILLSIES---EKSIG 280

  Fly   308 FDRQTAVI--IAMDLLFAGADPTLVTLGGILFSLSKSPDKQARLLEEIRGILPNKDSSLTIENMR 370
            |..|...|  :.:|:...|...:...|..|:..|.::|:...:|.:|||..:....|.:..:::.
plant   281 FQAQRDDIKFMILDMFIGGTSTSSTLLEWIMTELIRNPNVMKKLQDEIRSTIRPHGSYIKEKDVE 345

  Fly   371 NLPYLRACIKEGIRMYPIGPGTL-RRMPHDVVLSGYRVVAGTDVGIAANYQMANMEQFVPKVREF 434
            |:.||:|.|||..|::|..|..| |.:..||.:.||.:.|||:|.|.|.....:...:.|...||
plant   346 NMKYLKAVIKEVFRVHPPLPLILPRLLSEDVKVKGYNIAAGTEVIINAWAIQRDPAIWGPDAEEF 410

  Fly   435 IPERWLRDESNSHLVGETATPFMYLPFGFGPRSCAGKRIVDMMLEIAISRLVRNF 489
            .|||.|....:.|     .....::|||.|.|.|.|..:...::|:.::.||..|
plant   411 KPERHLDSTLDYH-----GKDLNFIPFGSGRRICPGINLALGLVEVTVANLVGRF 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12e1	NP_650003.4	p450	63..517	CDD:299894	110/462 (24%)
CYP71A12	NP_180633.3	CYP71-like	63..489	CDD:410695	109/451 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000