Protein Alignment Cyp12e1 and cyp27b1

DIOPT Version :9

• Sequence 1: NP_650003.4
• Gene: Cyp12e1 / 41272
• FlyBaseID: FBgn0037817
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001298720.1
• Gene: cyp27b1 / 793309
• ZFINID: ZDB-GENE-111005-2
• Length: 505
• Species: Danio rerio
• Alignment Length: 514
• Identity: 129/514 - (25%)
• Similarity: 233/514 - (45%)
• Gaps: 66/514 - (12%)

  Fly     1 MLSTQWNANKQISRQIYQLCRGLAQKATAVN---LEEAKPYADIPGPSKLQLIR-AFLPGGLYKN 61
            |:.....|.|...|....|.|...:.|..:.   ..:.|....:||||..:.|| .|:..|..:
Zfish     1 MMMVLHQALKVTGRSALPLLRFAERWADVIRAPPTPQVKTLEQMPGPSPARFIRDLFMKRGFSR- 64

  Fly    62 LPVHEMFLDMNRQYGSIFRMPSVAGTDLVLTMN---PQDYEVIFRNEGQYPYRRSFEV-MDYFKR 122
              :|::.|:..::||.:::    |....:||::   |:..:.:.|.|||:|.|..... .||  |
Zfish    65 --LHQLQLEGRQKYGPMWK----ASFGPILTVHVAEPELIQQVLRQEGQHPVRSELSSWKDY--R 121

  Fly   123 VHRREVFDGYDGLTSGNGPAWGKMRTAVNPILLQPRNAKLYMTNLVQVSDEFLERIRIIRDPVTQ 187
            ..|.|   || ||.:..|..|..:|:.::..:|:|:..:.|...|..|..:.|:::::.....:.
Zfish   122 ALRGE---GY-GLLTAEGEEWQCVRSLLSKHMLRPQAVEAYDGALNAVVSDLLQKLKLRSQESSS 182

  Fly   188 EMPDDFAVDIRHLVIESICSVALNTHLGLLGEQRNNKDIQKLVLALQDVVELGFQLDIMPAFW-- 250
            .:..|.:.:.....:|.|.||...:.:|.| :.....:.::.:.::..:..:......||. |
Zfish   183 RIVSDISAEFYRFGLEGISSVLFESRIGCL-DAVVPVETERFIQSINTMFVMTLLTMAMPQ-WLH 245

  Fly   251 KYLPMPNFKKLMRSLDTITDFCYFHIGNALKRIEEDAKAGT----------LNEIGLE-TSLLEK 304
            :.||.| :....|..|.:.:|...||...|:..::..:.|.          |::.||. ||:...
Zfish   246 RLLPKP-WDTFCRCWDVMFEFAKGHIDQRLQEEKQKLECGEQLEGRYLTYFLSQAGLPLTSVYSN 309

  Fly   305 LARFDRQTAVIIAMDLLFAGADPTLVTLGGILFSLSKSPDKQARLLEEIRGILPNKDSSL-TIEN 368
            :.            :||.||.|....||...|:.||:.||.|..|.:|:..::  ||.|: ...:
Zfish   310 VT------------ELLLAGVDTISSTLSWSLYELSRHPDVQTALRDEVLSVM--KDRSVPQASD 360

  Fly   369 MRNLPYLRACIKEGIRMYPIGPGTLRRMPHDVVLSGYRVVAGTDVGIAANYQMANMEQFVPKVRE 433
            :..:|.|:|.:||.:|:||:.|...|.:..|:.:.||.:...|.:.:.......:.:||    |:
Zfish   361 VAAMPLLKAVVKEILRLYPVIPANARVINKDIEVGGYVIPKNTLITLCHYATSRDPQQF----RD 421

  Fly   434 ---FIPERWLRDESNSHLVGETATPFMYLPFGFGPRSCAGKRIVDMMLEIAISRLVRNF 489
               |.|:||......||       |:..:|||.|.|||.|:||.::.:.:|:||::.:|
Zfish   422 PDSFRPQRWGDRSDRSH-------PYATVPFGVGKRSCIGRRIAELEVYLALSRILMHF 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12e1	NP_650003.4	p450	63..517	CDD:299894	113/448 (25%)
cyp27b1	NP_001298720.1	p450	45..493	CDD:278495	121/470 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48087
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6352
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.930