Protein Alignment Cyp12e1 and Cyp12c1

DIOPT Version :9

• Sequence 1: NP_650003.4
• Gene: Cyp12e1 / 41272
• FlyBaseID: FBgn0037817
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001287109.1
• Gene: Cyp12c1 / 40037
• FlyBaseID: FBgn0036806
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 491
• Identity: 201/491 - (40%)
• Similarity: 304/491 - (61%)
• Gaps: 9/491 - (1%)

  Fly    33 EEAKPYADIPGPSKLQLIRAFLPGGLYKNLPVHEMFLDMNRQYGSIFRMPSVAG-TDLVLTMNPQ 96
            |.|||:.::|||::.||.|.|..||.|..|.:.::.....:|:|.|..:|.:.| ...|.|.|.:
  Fly    36 EGAKPFTELPGPTRWQLFRGFQKGGEYHQLGMDDVMRLYKKQFGDICLIPGLFGMPSTVFTFNVE 100

  Fly    97 DYEVIFRNEGQYPYRRSFEVMDYFKRVHRREVFDGYDGLTSGNGPAWGKMRTAVNPILLQPRNAK 161
            .:|.::|.|||:|.|...|.:.:::...:.|.|....|| .|||..|||.|:||||:|:|.||..
  Fly   101 TFEKVYRTEGQWPVRGGAEPVIHYRNKRKDEFFKNCMGL-FGNGAEWGKNRSAVNPVLMQHRNVA 164

  Fly   162 LYMTNLVQVSDEFLERIRIIRDPVTQEMPDDFAVDIRHLVIESICSVALNTHLGLLGEQRNNKDI 226
            :|:..:.:|:.:|:.|||.|||..:||:|.||...|.||..||:.:|||:..||||.|.....:.
  Fly   165 IYLKPMQRVNRQFVNRIREIRDKESQEVPGDFMNTINHLTFESVATVALDRELGLLREANPPPEA 229

  Fly   227 QKLVLALQDVVELGFQLDIMPAFWKYLPMPNFKKLMRSLDTITDFCYFHIGNALKRIEEDAKAGT 291
            .||...::.:::..|.|.:.|:.::|:|.|.:||..|::|.|.|.|..::..|::||:..:..|.
  Fly   230 SKLFKNIEVLMDSFFDLGVRPSLYRYIPTPTYKKFSRAMDEIFDTCSMYVNQAIERIDRKSSQGD 294

  Fly   292 LNEIGLETSLLEKLARFDRQTAVIIAMDLLFAGADPTLVTLGGILFSLSKSPDKQARLLEEIRGI 356
            .|:   ..|:||:|.:.||:.||::|||:|..|.|.|...:.|||.:|:|:|:||.||.||:...
  Fly   295 SND---HKSVLEQLLQIDRKLAVVMAMDMLMGGVDTTSTAISGILLNLAKNPEKQQRLREEVLSK 356

  Fly   357 LPNKDSSLTIENMRNLPYLRACIKEGIRMYPIGPGTLRRMPHDVVLSGYRVVAGTDVGIAANYQM 421
            |.:..|..|:|:|::||||||.|||.:|:||:..|..|....||||.|||:..||.: :..|..:
  Fly   357 LTSLHSEFTVEDMKSLPYLRAVIKESLRLYPVTFGNARSAGADVVLDGYRIPKGTKL-LMTNSFL 420

  Fly   422 ANMEQFVPKVREFIPERWLR---DESNSHLVGETATPFMYLPFGFGPRSCAGKRIVDMMLEIAIS 483
            ...::..|:.:|||||||||   |:.:..|:.:....|:|||||||||.|.||||||:.:|:.::
  Fly   421 LKDDRLYPRAKEFIPERWLRRKDDDKSDVLMNKDLNAFIYLPFGFGPRMCVGKRIVDLEMELTVA 485

  Fly   484 RLVRNFKIGFDYPIENAFKAQFFVQPNIPFKFKFIE 519
            .|||||.|.::|..|..:|.:|..:||||.||||.:
  Fly   486 NLVRNFHIEYNYSTEKPYKCRFLYKPNIPLKFKFTD 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12e1	NP_650003.4	p450	63..517	CDD:299894	184/457 (40%)
Cyp12c1	NP_001287109.1	p450	45..502	CDD:278495	187/461 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445006
Domainoid	1	1.000	199	1.000	Domainoid score	I1783
eggNOG	1	0.900	-	-		E2759_KOG0159
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	201	1.000	Inparanoid score	I3768
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	1	1.000	-	-		FOG0000720
OrthoInspector	1	1.000	-	-		mtm6352
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24305
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
	10	9.900