Protein Alignment Cyp12e1 and Cyp12b2

DIOPT Version :9

• Sequence 1: NP_650003.4
• Gene: Cyp12e1 / 41272
• FlyBaseID: FBgn0037817
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Alignment Length: 520
• Identity: 186/520 - (35%)
• Similarity: 298/520 - (57%)
• Gaps: 21/520 - (4%)

  Fly     6 WNANKQISRQIYQLCR-GLAQKATAVNLEEAKPYADIPGPSKLQLIRAFLPGGLYKNLPVHEMFL 69
            :|.|..:...:.|..: .||........::|:.:.:|||||.|:::..|:|||..:|..:.:|..
  Fly    20 FNRNSSVGGTLSQQTQLELADSRIDEKWQQARSFGEIPGPSLLRMLSFFMPGGALRNTNLIQMNR 84

  Fly    70 DMNRQYGSIFRMPSVAG-TDLVLTMNPQDYEVIFRNEGQYPYRRSFEVMDYFKRVHRREVFDGYD 133
            .|...||.|:.:|.:.| .:.|.|.||.|:|:.:||||.:|.|...|.::|::::||.:||.|..
  Fly    85 LMREMYGDIYCIPGMMGKPNAVFTYNPDDFEMTYRNEGVWPIRIGLESLNYYRKIHRPDVFKGVG 149

  Fly   134 GLTSGNGPAWGKMRTAVNPILLQPRNAKLYMTNLVQVSDEFLERIRIIRDPVTQEMPDDFAVDIR 198
            ||.|..|..|..:|..|||:|::.:|.:..:..|.|:|.||::::...|:|.|..:..||...::
  Fly   150 GLASDQGQEWADIRNKVNPVLMKVQNVRQNLPQLDQISKEFIDKLETQRNPETHTLTTDFHNQLK 214

  Fly   199 HLVIESICSVALNTHLGLLGEQRN-NKDIQKLVLALQDVVELGFQLDIMPAFWKYLPMPNFKKLM 262
            ....|||..|||||.:|||.:..: |.|  :|...::|.....||.|:.|:.|.:.....|||.:
  Fly   215 MWAFESISFVALNTRMGLLSDNPDPNAD--RLAKHMRDFFNYSFQFDVQPSIWTFYKTAGFKKFL 277

  Fly   263 RSLDTITDFCYFHIGNALKRIEEDAKAGTLNEIGLETSLLEKLARFDRQTAVIIAMDLLFAGADP 327
            ::.|.|||....:|..|::...:       |:.|....:||:|...:::.||.:.||:|.||.|.
  Fly   278 KTYDNITDITSNYIETAMRGFGK-------NDDGKTKCVLEQLLEHNKKVAVTMVMDMLMAGIDT 335

  Fly   328 TLVTLGGILFSLSKSPDKQARLLEEIRGILPNKDSSLTIENMRNLPYLRACIKEGIRMYPIGPGT 392
            |......||:.|:::|.||.:|..|:..|||....|||.:|.:|:||||||||||:|:..|.||.
  Fly   336 TSSACLTILYHLARNPSKQEKLRRELLRILPTTKDSLTDQNTKNMPYLRACIKEGLRITSITPGN 400

  Fly   393 LRRMPHDVVLSGYRVVAGTDVGIAANYQMANMEQFVPKVREFIPERWLRDESNSHL----VGETA 453
            .|..|.|:|||||:|..||.| :....:::|.:::..:..||||||||:.:....:    ...|.
  Fly   401 FRITPKDLVLSGYQVPRGTGV-LMGVLELSNDDKYFAQSSEFIPERWLKSDLAPDIQACPAARTR 464

  Fly   454 TPFMYLPFGFGPRSCAGKRIVDMMLEIAISRLVRNFKIGF--DYPIENAFKAQFFVQPNIPFKFK 516
            .||:|||||||||:|.||||.::.:|..:.||:|::|:.:  :.|||  :::...:.|....:||
  Fly   465 NPFVYLPFGFGPRTCIGKRIAELEIETLLVRLLRSYKVSWLPETPIE--YESTIILSPCGDIRFK 527

  Fly   517  516
              Fly   528  527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12e1	NP_650003.4	p450	63..517	CDD:299894	169/462 (37%)
Cyp12b2	NP_611370.2	p450	59..511	CDD:299894	172/461 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445020
Domainoid	1	1.000	199	1.000	Domainoid score	I1783
eggNOG	1	0.900	-	-		E2759_KOG0159
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	201	1.000	Inparanoid score	I3768
Isobase	1	0.950	-	0	Normalized mean entropy	S4820
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	1	1.000	-	-		FOG0000720
OrthoInspector	1	1.000	-	-		mtm6352
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24305
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
	11	10.850