Protein Alignment Cyp12e1 and Cyp12d1-p

DIOPT Version :10

• Sequence 1: NP_650003.4
• Gene: Cyp12e1 / 41272
• FlyBaseID: FBgn0037817
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_610635.4
• Gene: Cyp12d1-p / 246648
• FlyBaseID: FBgn0050489
• Length: 521
• Species: Drosophila melanogaster
• Alignment Length: 497
• Identity: 207/497 - (41%)
• Similarity: 306/497 - (61%)
• Gaps: 9/497 - (1%)

  Fly    25 QKATAVNLEEAKPYADIPGPSKLQLIRAFLPGGLYKNLPVHEMFLDMNRQYGSIFRMPSVAG-TD 88
            ::|.:...||.|.|.:||.|:|.:.:|||:|||.::|..:.|....|.::||.|:.||.:.| .|
  Fly    29 EQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKD 93

  Fly    89 LVLTMNPQDYEVIFRNEGQYPYRRSFEVMDYFKRVHRREVFDGYDGLTSGNGPAWGKMRTAVNPI 153
            .|.|.|.:|.|::|||||.:|.|...:.:.||:...|.:|:....||.:....||||:|:|:|||
  Fly    94 WVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPI 158

  Fly   154 LLQPRNAKLYMTNLVQVSDEFLERIRIIRDPVTQEMPDDFAVDIRHLVIESICSVALNTHLGLLG 218
            .:|||..::|...|..:::||:|||:.||||.|.|:|:||..:|..||.||:..||.:..:||:.
  Fly   159 FMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIR 223

  Fly   219 EQRNNKDIQKLVLALQDVVELGFQLDIMPAFWKYLPMPNFKKLMRSLDTITDFCYFHIGNALKRI 283
            :.|:|.|...|....:|:..|.|:|||.|:.||.:..|.::|:.|:|:...:.....:......:
  Fly   224 KNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVAQKMLKENQDAL 288

  Fly   284 EEDAKAG-TLNEIGLETSLLEKLARFDRQTAVIIAMDLLFAGADPTLVTLGGILFSLSKSPDKQA 347
            |:..:|| .:|    ..|:||:|...|.:.|||:::|:||||.|.|...|..:|..|||.|||||
  Fly   289 EKRRQAGEKIN----SNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQA 349

  Fly   348 RLLEEIRGILPNKDSSLTIENMRNLPYLRACIKEGIRMYPIGPGTLRRMPHDVVLSGYRVVAGTD 412
            :|.||:..|:|.|||.|..|||:::|||||.|||.:|.||.|.||:|...:||:||||||..||.
  Fly   350 KLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGLGTMRTCQNDVILSGYRVPKGTT 414

  Fly   413 VGIAANYQMANMEQFVPKVREFIPERWLRDESNSHLVGETATPFMYLPFGFGPRSCAGKRIVDMM 477
            |.:.:|..|.. ..:.|:..||:|||||||......:  ..:||.:||||||||.|.|||:||:.
  Fly   415 VLLGSNVLMKE-ATYYPRPDEFLPERWLRDPETGKKM--QVSPFTFLPFGFGPRMCIGKRVVDLE 476

  Fly   478 LEIAISRLVRNFKIGFDYPIENAFKAQFFVQPNIPFKFKFIE 519
            :|..:::|:|||.:.|:......||..|.::|.|.|.|||.:
  Fly   477 METTVAKLIRNFHVEFNRDASRPFKTMFVMEPAITFPFKFTD 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12e1	NP_650003.4	CYP24A1-like	73..514	CDD:410677	185/442 (42%)
Cyp12d1-p	NP_610635.4	CYP24A1-like	76..508	CDD:410677	183/438 (42%)