Protein Alignment Cyp12e1 and cyp-13A1

DIOPT Version :9

• Sequence 1: NP_650003.4
• Gene: Cyp12e1 / 41272
• FlyBaseID: FBgn0037817
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001369869.1
• Gene: cyp-13A1 / 188361
• WormBaseID: WBGene00011677
• Length: 519
• Species: Caenorhabditis elegans
• Alignment Length: 488
• Identity: 117/488 - (23%)
• Similarity: 190/488 - (38%)
• Gaps: 72/488 - (14%)

  Fly    41 IPGPSKLQLIRAFLPGGLYKNLPVHEMFLDMNRQYGSIFRMPSVAGTDLVLTMNPQDYEVIFRNE 105
            :.||....::..|| ..|..|.|......:..:::|.|:.........||::.....:||.....
 Worm    32 VVGPMGFPVLGVFL-NSLDNNFPFPLQCREWTKKFGKIYGFTEGTLKTLVISDPELVHEVFVTQY 95

  Fly   106 GQYPYRRSFEVMDYFKRVHRREVFDGYDGLTSGNGPAWGKMRTAVNPILLQPRNAKLYMTNLVQV 170
            ..:..|:...:....::..|..:|       :..|..|.::|...:|........|||.|    |
 Worm    96 DNFYGRKRNPIQGDSEKEKRTNLF-------AAQGFRWKRLRAISSPTFSNSSLRKLYQT----V 149

  Fly   171 SDEFLERIRIIRDPVTQEMPDDFAVDIRHLVIESICSVALNTHLGLLGEQRNNKDIQKLVLAL-- 233
            .|..||.:|.|..........|.....:...::.|..:|    :|....|.....|..:|..|
 Worm   150 EDSALELLRHIEKQSAGGKQIDMLKFYQEFTLDVIGRIA----MGQTDSQMFKNPIMPIVSKLFQ 210

  Fly   234 QDVVELGFQLDIMPAF---------WKYLPMPNFKKLMR-SLDTITDFCYFHIGNALKRIEEDAK 288
            .:..:|.....|.|.|         .|.|.:.:|:|:.. :||.|      |  |.:|:.|||.|
 Worm   211 GNFAKLFLIGGIFPTFLVEIIRQILLKNLKVGSFRKINEITLDAI------H--NRIKQREEDQK 267

  Fly   289 AGTLNEIGLETSLL--------EKLARF--------------DRQ--TAVIIAMDLLF--AGADP 327
            .|.  |||.....:        |.:..|              :||  |..|:....:|  ||.|.
 Worm   268 NGI--EIGEPADFIDLFLDAKAEDVEHFGENNGDFSKSTTYTNRQLTTEEIVGQCTVFLIAGFDT 330

  Fly   328 TLVTLGGILFSLSKSPDKQARLLEEIRGILPNKDSSLTIENMRNLPYLRACIKEGIRMYPIGP-G 391
            |.::|....:.|:..|:.|.:|.||:....||.:  :||:.:..|.|:....||.:|:||:|. .
 Worm   331 TALSLSYATYLLATHPEIQKKLQEEVNRECPNPE--VTIDQLSKLKYMECVFKEALRLYPLGAFA 393

  Fly   392 TLRRMPHDVVLSGYRVVAGTDVGIAANYQMANMEQFVPKVREFIPERWLRDESNSHLVGETATPF 456
            ..||...:..|...:|..||.:.:.......:...:.....:|.||||  ...||..:.:.:.
 Worm   394 NSRRCMRNTKLGNMKVEVGTMIQVDTWTLHTDPNIWGDDAEDFKPERW--QTPNSDQIYQKSG-- 454

  Fly   457 MYLPFGFGPRSCAGKRIVDMMLEIAISRLVRNF 489
             |:|||.|||.|.|.|:..|..:|.:..::|.|
 Worm   455 -YIPFGLGPRQCIGMRLAYMEEKILLVHILRKF 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12e1	NP_650003.4	p450	63..517	CDD:299894	111/466 (24%)
cyp-13A1	NP_001369869.1	CYP3A-like	64..510	CDD:410678	110/455 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4820
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.860