Protein Alignment Cyp12e1 and Cyp11a1

DIOPT Version :9

• Sequence 1: NP_650003.4
• Gene: Cyp12e1 / 41272
• FlyBaseID: FBgn0037817
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_062753.3
• Gene: Cyp11a1 / 13070
• MGIID: 88582
• Length: 526
• Species: Mus musculus
• Alignment Length: 511
• Identity: 127/511 - (24%)
• Similarity: 221/511 - (43%)
• Gaps: 55/511 - (10%)

  Fly    26 KATAVNLEEAKPYADIPGPSK---LQLIRAFLPGGLYKNLPVHEMFLDMNRQYGSIFRMPSVAGT 87
            |....:....:.:.:||.|..   |.|...:...|..|   :|...:...::||.|:|  ...||
Mouse    33 KGAGTSTSSPRSFNEIPSPGDNGWLNLYHFWRESGTQK---IHYHQMQSFQKYGPIYR--EKLGT 92

  Fly    88 -DLVLTMNPQDYEVIFRNEGQYPYRRSFEVMDYFKRVHRREVFDGYDGLTSGNGPAWGKMRTAVN 151
             :.|..::|:|..::|..||..|.|........:.:.::|.:     |:...:..||.|.|..:|
Mouse    93 LESVYIVDPKDASILFSCEGPNPERFLVPPWVAYHQYYQRPI-----GVLFKSSDAWKKDRIVLN 152

  Fly   152 PILLQPRNAKLYMTNLVQVSDEFLERIRIIRDPVTQEMPDDF----AVDIRHLVIESICSVALNT 212
            ..::.|...|.::..|..|:.:|   |:::...:.|:...:|    :.|:.....|||.||....
Mouse   153 QEVMAPGAIKNFVPLLEGVAQDF---IKVLHRRIKQQNSGNFSGVISDDLFRFSFESISSVIFGE 214

  Fly   213 HLGLLGEQRNNKDIQKLVLALQDVVELGF-QLDIMPAFWKYLPMPNFKK-------LMRSLDTIT 269
            .:|:| |:..:.:.|:.:.|:..:..... .|::.|.|::.|....:|.       :....|..|
Mouse   215 RMGML-EEIVDPEAQRFINAVYQMFHTSVPMLNLPPDFFRLLRTKTWKDHAAAWDVIFNKADEYT 278

  Fly   270 DFCYFHIGNALKRIEEDAKAGTLNEIGLETSLL--EKLARFDRQTAVIIAMDLLFAGADPTLVTL 332
            ...|:.:     |.:.|..    ...|:..|||  .||...:.|..:   .::|..|.|.|.:||
Mouse   279 QNFYWDL-----RQKRDFS----QYPGVLYSLLGGNKLPFKNIQANI---TEMLAGGVDTTSMTL 331

  Fly   333 GGILFSLSKSPDKQARLLEEIRGILPNKDSSLTIENMRNL-PYLRACIKEGIRMYPIGPGTLRRM 396
            ...|:.::.:...|..|..|:  :...:.:...:..|..| |.|:|.|||.:|::||.....|..
Mouse   332 QWNLYEMAHNLKVQEMLRAEV--LAARRQAQGDMAKMVQLVPLLKASIKETLRLHPISVTLQRYT 394

  Fly   397 PHDVVLSGYRVVAGTDVGIAANYQMANMEQFVPKVREFIPERWLRDESNSHLVGETATPFMYLPF 461
            .:|:||..|::.|.|.|.: |::.|.....|.|...:|.|.|||....|:       |.|.||.|
Mouse   395 VNDLVLRNYKIPAKTLVQV-ASFAMGRDPGFFPNPNKFDPTRWLEKSQNT-------THFRYLGF 451

  Fly   462 GFGPRSCAGKRIVDMMLEIAISRLVRNFKIGFDYPIENAFKAQFFVQPNIPFKFKF 517
            |:|.|.|.|:||.::.:.|.:..|:.||:|......:...|....:.|..|..|.|
Mouse   452 GWGVRQCLGRRIAELEMTILLINLLENFRIEVQNLRDVGTKFSLILMPENPILFNF 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12e1	NP_650003.4	p450	63..517	CDD:299894	118/469 (25%)
Cyp11a1	NP_062753.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..49		1/15 (7%)
		p450	49..507	CDD:278495	124/493 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	196	1.000	Inparanoid score	I3800
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8705
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.870