Protein Alignment Cyp12e1 and cyp24a1

DIOPT Version :9

• Sequence 1: NP_650003.4
• Gene: Cyp12e1 / 41272
• FlyBaseID: FBgn0037817
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: XP_012808417.2
• Gene: cyp24a1 / 100497429
• XenbaseID: XB-GENE-479201
• Length: 508
• Species: Xenopus tropicalis
• Alignment Length: 510
• Identity: 144/510 - (28%)
• Similarity: 239/510 - (46%)
• Gaps: 53/510 - (10%)

  Fly    27 ATAV-NLEEAK-------PY--ADIPGPSKLQLIRAFL----PGGLYKNLPVHEMFLDMNRQYGS 77
            |||| :|:|.:       |:  |.:|||:||.::.:.|    .|||.:.   ||.....::|:|.
 Frog    28 ATAVCDLKEEELPAPSSCPHSLAALPGPTKLPILGSLLDILRKGGLKRQ---HEALASYHKQFGK 89

  Fly    78 IFRMPSVAGTDLVLTMNPQDYEVIFRNEGQYPYRRSFEVMDYFKRVHRREVFDGYDGLTSGNGPA 142
            |||| .:...|.|....|...|.::|.|..||.|...:....: |.:|.|.:    ||....|..
 Frog    90 IFRM-KLGSFDSVHIGAPCLLEALYREESNYPKRLEIKPWKAY-RDYRDEAY----GLLILEGKD 148

  Fly   143 WGKMRTAVNPILLQPRNAKLYMTNLVQVSDEFLERIRIIRDPVTQE--MPDDFAVDIRHLVIESI 205
            |.::|:|....|::|.......|.:.:|..:|::||    |.|..|  ..:|...::....:|||
 Frog   149 WQRVRSAFQQKLMKPTEVGKLDTKINEVLVDFMKRI----DSVCDEDGTIEDLYCELNKWSLESI 209

  Fly   206 CSVALNTHLGLLGEQRN-NKDIQKLVLALQDVVE-LGFQLDIMPAFWKYLPMPNFKKLMRSLDTI 268
            |.|......|.|  |.| .::.|..:.|::.::. .|..:.......|.|....:|....:.|:|
 Frog   210 CLVLYEKRFGFL--QPNLGEEAQNFITAIKMMMSTFGLMMVTPVELHKSLNTKIWKDHTHAWDSI 272

  Fly   269 TDFCYFHIGNALKRIEEDAKAGTLNEIGLETSLLEKLARFDRQTAVIIAMDLLFAGADPTLVTLG 333
            ......||...|.::........|..|..::.|.:|     ...|.|  .::|....:.|..:|.
 Frog   273 FKTAKCHIDRRLTKLSSKGSEDFLCTIYNDSKLSKK-----EMYATI--TEMLIGAVETTANSLL 330

  Fly   334 GILFSLSKSPDKQARLLEEIRGI-LPNKDSSLTIENMRNLPYLRACIKEGIRMYPIGPGTLRRMP 397
            ..:|::|::|..|.:|||||..: ||  |...|.:::||:|||:||:||.:|:.|..|.|.|.:.
 Frog   331 WAIFNISRNPHIQKKLLEEIESVLLP--DQVPTADDIRNMPYLKACLKESMRITPSIPFTTRTLD 393

  Fly   398 HDVVLSGYRVVAGTDVGIAANYQMANMEQFVPKVREFIPERWLRDESNSHLVGETATPFMYLPFG 462
            .:.||..|.:..||.:.|.::...:|.|.| ....:|.|||||:.::       |..||.::|||
 Frog   394 KETVLGDYVLPKGTVLTINSHVLGSNQECF-DNWNQFRPERWLQQKN-------TINPFAHVPFG 450

  Fly   463 FGPRSCAGKRIVDMMLEIAISRLVRNFKI--GFDYPIENAFKAQFFVQPNIPFKF 515
            .|.|.|.|:|:.::.|::.:..|:|.::|  ..:.|:|............:|..|
 Frog   451 IGKRMCIGRRLAELQLQLTLCWLIRKYEIVATDNDPVETLHLGTLMPSRELPVAF 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12e1	NP_650003.4	p450	63..517	CDD:299894	127/460 (28%)
cyp24a1	XP_012808417.2	CYP24A1	84..502	CDD:410738	123/446 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	193	1.000	Domainoid score	I3126
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	208	1.000	Inparanoid score	I3591
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	1	1.000	-	-		FOG0000720
OrthoInspector	1	1.000	-	-		mtm9361
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.970