Protein Alignment CG6345 and miaB

DIOPT Version :10

• Sequence 1: NP_650002.1
• Gene: CG6345 / 41271
• FlyBaseID: FBgn0037816
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_415194.1
• Gene: miaB / 945260
• ECOCYCID: G6364
• Length: 474
• Species: Escherichia coli
• Alignment Length: 494
• Identity: 171/494 - (34%)
• Similarity: 263/494 - (53%)
• Gaps: 48/494 - (9%)

  Fly    92 RKVHFEVYGCQMNTNDTEVVFSIL-KENGYLRCQEPEEADVIMLVTCAVRDGAEQRIRNRLKHLR 155
            :|:|.:.:|||||..|:..:..:| ..:||......|||||::|.||::|:.|::::.::|...:
E. coli     3 KKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVLLLNTCSIREKAQEKVFHQLGRWK 67

  Fly   156 AMKNKRSTRRHPLQLTLLGCMAERLKEKLLEQEQCVDVIAGPDSYKDLPRLLAISRHYGNSAINV 220
            .:|.|..    .|.:.:.||:|.:..|.:.::...||:|.||.:...||.::...|...:..:::
E. coli    68 LLKEKNP----DLIIGVGGCVASQEGEHIRQRAHYVDIIFGPQTLHRLPEMINSVRGDRSPVVDI 128

  Fly   221 LLSLDETYADVMPVRLNSESPTAFVSIMRGCDNMCTYCIVPFTRGRERSRPLASIVAEVKALAEQ 285
            .....|.: |.:| ...:|.||||||||.||:..||||:||:|||.|.|||...|:.|:..||.|
E. coli   129 SFPEIEKF-DRLP-EPRAEGPTAFVSIMEGCNKYCTYCVVPYTRGEEVSRPSDDILFEIAQLAAQ 191

  Fly   286 GVKEVTLLGQNVNSYRDRTAQEEQDSLKATPVPGFSTVYKPKTGGTPFAALLRSVAQAVPDMRIR 350
            ||:||.|||||||::|...                   |...||.  ||.|||.||......|||
E. coli   192 GVREVNLLGQNVNAWRGEN-------------------YDGTTGS--FADLLRLVAAIDGIDRIR 235

  Fly   351 FTSPHPKDFSDEVLEVIRDHPNVCKQLHLPAQSGNTQVLERMRRGYSREAYLELVQHIRQFLPNV 415
            ||:.||.:|:|:::||.||.|.:...||||.|||:.::|..|.|.::...|..:::.:|...|::
E. coli   236 FTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNLMGRTHTALEYKAIIRKLRAARPDI 300

  Fly   416 GLSSDFICGFCGETEEEFQDTVSLIQQVQYNVAYLFAYSMREKTTAHRRYKDDVPINVKNERLQR 480
            .:|||||.||.|||.|:|:.|:.||..|.::::|.|.:|.|..|.| ....||||...|.:||..
E. coli   301 QISSDFIVGFPGETTEDFEKTMKLIADVNFDMSYSFIFSARPGTPA-ADMVDDVPEEEKKQRLYI 364

  Fly   481 MVQVFREGATQLHRKMEGQEQLILIEGKSKRSDAHWFGRNDAN---------------IKVIVPS 530
            :.:...:.|....|:|.|..|.||:||.|::|.....||.:.|               :.|.:..
E. coli   365 LQERINQQAMAWSRRMLGTTQRILVEGTSRKSIMELSGRTENNRVVNFEGTPDMIGKFVDVEITD 429

  Fly   531 IYVPISGDSTARKSFGVGDFLAVRIEESNSQVLKGTPLE 569
            :|    .:|...|.....|.:.:|:.|:...|:..|..|
E. coli   430 VY----PNSLRGKVVRTEDEMGLRVAETPESVIARTRKE 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6345	NP_650002.1	MiaB	91..569	CDD:440386	170/492 (35%)
miaB	NP_415194.1	miaB-methiolase	4..440	CDD:273700	165/467 (35%)