DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6345 and AT4G36390

DIOPT Version :9

Sequence 1:	NP_650002.1	Gene:	CG6345 / 41271	FlyBaseID:	FBgn0037816	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_195357.2	Gene:	AT4G36390 / 829791	AraportID:	AT4G36390	Length:	640	Species:	Arabidopsis thaliana

Alignment Length:	594	Identity:	276/594 - (46%)
Similarity:	377/594 - (63%)	Gaps:	39/594 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 HASTTAS-------KGATTSVTSSAAGQLK--SEPAARATFLERIQR-----GPGFQDFFAVKPA 64
            |||:::|       :.:|..:|.....:.|  |...:|:..:.:|..     ||....|.:...|
plant    42 HASSSSSSALLPRCRSSTHRLTQKPINRKKGFSLNLSRSFSISQIASSGKFDGPSLHQFVSNAQA 106

  Fly    65 -SRLKTDEEEHVDTSVPYLNSIDFNGNGRKVHFEVYGCQMNTNDTEVVFSILKENGYLR-CQEPE 127
             :.|.|.|.|...|    |:| |....|| ::.|.||||||.||.|:|.:|:|.:||.. ..:||
plant   107 HASLTTPETESEST----LDS-DIASKGR-IYHETYGCQMNINDMEIVLAIMKNSGYKEVVTDPE 165

  Fly   128 EADVIMLVTCAVRDGAEQRIRNRLKHLRAMKNK--------RSTRRHPLQLTLLGCMAERLKEKL 184
            .|:||.:.|||:|:.||||:..||.:...:|.:        |:....|.::.:|||||||||:|:
plant   166 SAEVIFVNTCAIRENAEQRVWQRLNYFWFLKREWKVNAATGRAKSLKPPKVVVLGCMAERLKDKI 230

  Fly   185 LEQEQCVDVIAGPDSYKDLPRLLAISRHYGNSAINVLLSLDETYADVMPVRLNSESPTAFVSIMR 249
            |:.::.|||:.|||:|:||||||. ...||...||.||||:|||||:.|||::..|.|||||:||
plant   231 LDSDKMVDVVCGPDAYRDLPRLLE-EVDYGQKGINTLLSLEETYADISPVRISENSITAFVSVMR 294

  Fly   250 GCDNMCTYCIVPFTRGRERSRPLASIVAEVKALAEQGVKEVTLLGQNVNSYRDRTAQEEQDSLKA 314
            ||:|||.:||||||||||||||:.||:.||..|.|.|||||||||||||||.|.:|..|..: ..
plant   295 GCNNMCAFCIVPFTRGRERSRPVESIIREVGELWESGVKEVTLLGQNVNSYNDDSADRESGA-NW 358

  Fly   315 TPVPGFSTVYKPKTGGTPFAALLRSVAQAVPDMRIRFTSPHPKDFSDEVLEVIRDHPNVCKQLHL 379
            ....|||:..|.|..|..||.||..::...|:||.|||||||||:.||:|.::||..|:|..:||
plant   359 EYSEGFSSRCKVKNMGLRFADLLDRLSVEFPEMRFRFTSPHPKDYPDELLYLMRDRHNICNLIHL 423

  Fly   380 PAQSGNTQVLERMRRGYSREAYLELVQHIRQFLPNVGLSSDFICGFCGETEEEFQDTVSLIQQVQ 444
            ||||||:::||:|||||:|||||:||:.||..:|:|.::||||.|||||||||.|:|:||::.|.
plant   424 PAQSGNSRILEQMRRGYTREAYLDLVKKIRSIIPDVAITSDFITGFCGETEEEHQETLSLVRAVG 488

  Fly   445 YNVAYLFAYSMREKTTAHRRYKDDVPINVKNERLQRMVQVFREGATQLHRKMEGQEQLILIEGKS 509
            |::||:|||||||||.|||.|.||||..||..||..::..|||.....:....|..||:|:||.:
plant   489 YDMAYMFAYSMREKTHAHRNYTDDVPEEVKQRRLTELIDAFRETTGPCYDSQVGSTQLVLVEGPN 553

  Fly   510 KRS-DAHWFGRNDANIKV--IVPSIY---VPISGDSTARKSFGVGDFLAVRIEESNSQVLKGTPL 568
            ||: :....|:.|...:|  :...::   ..:.||...|.. |:|||:.|:||:|....|.|..|
plant   554 KRAPETELIGKTDKGHRVSFVTKPLFDKACLLDGDDLKRNP-GIGDFVEVQIEKSTRASLFGEAL 617

  Fly   569 ELSNITDFH 577
            .:|.::.||
plant   618 AISKMSLFH 626

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6345	NP_650002.1	PRK14329	88..570	CDD:237676	251/496 (51%)
		UPF0004	93..196	CDD:279287	47/111 (42%)
		TRAM	494..568	CDD:280171	24/79 (30%)
AT4G36390	NP_195357.2	PRK14329	130..616	CDD:237676	249/489 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	242	1.000	Domainoid score	I580
eggNOG	1	0.900	-	-		E1_COG0621
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9502
Inparanoid	1	1.050	485	1.000	Inparanoid score	I333
OMA	1	1.010	-	-		QHG54971
OrthoDB	1	1.010	-	-		D835984at2759
OrthoFinder	1	1.000	-	-		FOG0005052
OrthoInspector	1	1.000	-	-		oto2911
orthoMCL	1	0.900	-	-		OOG6_102063
Panther	1	1.100	-	-	LDO	PTHR43020
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3577
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840