Protein Alignment Rrp46 and EXOSC4

DIOPT Version :9

• Sequence 1: NP_650001.2
• Gene: Rrp46 / 41270
• FlyBaseID: FBgn0037815
• Length: 233
• Species: Drosophila melanogaster
• Sequence 2: NP_061910.1
• Gene: EXOSC4 / 54512
• HGNCID: 18189
• Length: 245
• Species: Homo sapiens
• Alignment Length: 144
• Identity: 39/144 - (27%)
• Similarity: 63/144 - (43%)
• Gaps: 31/144 - (21%)

  Fly    13 KLRQMHCEFNPLSRCDGSVMYSQGATGLIGAVLGPIEVKTQNLSI--DGSYLECNY--------- 66
            :||::.......::.|||....||.|..:..|.||.|::......  |.:.:.|.|
Human    21 ELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHEIRGSRARALPDRALVNCQYSSATFSTGE 85

  Fly    67 ---RP-------KAGLPQVTDRIREAAIRDVLELALLSEAHPRSKMSVQIQELEDRGSIDACAVN 121
               ||       :.||          .:|...|.|:|::.||||::.:.:|.|:..|...|..||
Human    86 RKRRPHGDRKSCEMGL----------QLRQTFEAAILTQLHPRSQIDIYVQVLQADGGTYAACVN 140

  Fly   122 CACLAMLIGGLPLK 135
            .|.||:|..|:|::
Human   141 AATLAVLDAGIPMR 154

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rrp46	NP_650001.2	Rph	10..215	CDD:223761	39/144 (27%)
		RNase_PH_RRP46	14..211	CDD:206777	39/143 (27%)
EXOSC4	NP_061910.1	RNase_PH_RRP41	11..237	CDD:206775	39/144 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0689
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53663
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820