DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rrp46 and exos-4.1

DIOPT Version :9

Sequence 1:	NP_650001.2	Gene:	Rrp46 / 41270	FlyBaseID:	FBgn0037815	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	NP_001366781.1	Gene:	exos-4.1 / 24105309	WormBaseID:	WBGene00007201	Length:	240	Species:	Caenorhabditis elegans

Alignment Length:	207	Identity:	49/207 - (23%)
Similarity:	91/207 - (43%)	Gaps:	14/207 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 KLRQMHCEFNPLSRCDGSVMYSQGATGLIGAVLGPIEVKTQNLSIDGSYLECNYRPK--AGLPQV 75
            ::|.::.........:||.....|.|.::.||.||.|.|:.....|...:.|.|...  :||.:.
Worm    18 QIRNINTRLGLNRNAEGSCYLEHGNTKVLCAVYGPYEGKSSKRIEDKCAIVCQYSATKFSGLERK 82

  Fly    76 T----DRIREAAIRDVLELA----LLSEAHPRSKMSVQIQELEDRGSIDACAVNCACLAMLIGGL 132
            .    || :...|..:||.|    :|:||.|||::.:..:.::..||..|..||...||:...|:
Worm    83 NRTRGDR-KSTEISRLLEKAFESVILTEAFPRSQLDIFCEVIQGDGSNLAACVNATSLALADAGI 146

  Fly   133 PLK-YSFAAVHAIINEQGEYVLDPDQSETLHQRASFTFAFDSVEGNLLLIQTKGSFKIAQFNDIE 196
            |:| .:.||...:::  |:.::|....|........|.|.......::|::.:....|...:.:.
Worm   147 PMKGIASAATCGVVD--GKPIVDLTSREETDLLPRVTLATICGRDEVILVELQNRLHIDHLSTVM 209

  Fly   197 CLCLAASAEIFQ 208
            ....|..|::::
Worm   210 DAAKATCADVYE 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rrp46	NP_650001.2	Rph	10..215	CDD:223761	49/207 (24%)
Rrp46	NP_650001.2	RNase_PH_RRP46	14..211	CDD:206777	49/206 (24%)
exos-4.1	NP_001366781.1	RNase_PH_RRP41	8..232	CDD:206775	49/207 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53663
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920