DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rrp46 and crn-5

DIOPT Version :9

Sequence 1:	NP_650001.2	Gene:	Rrp46 / 41270	FlyBaseID:	FBgn0037815	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	NP_496284.1	Gene:	crn-5 / 174634	WormBaseID:	WBGene00000798	Length:	214	Species:	Caenorhabditis elegans

Alignment Length:	216	Identity:	62/216 - (28%)
Similarity:	101/216 - (46%)	Gaps:	34/216 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 KLRQMHCEFNPLSRCDGSVMYSQGATGLIGAVLGPIEVKTQNLSIDGSYLECNYRPKAGLPQVTD 77
            :||:|.||.:.|...|||..:|||||.:..:..||.:|.....|.:...|:.:||...|..:.
Worm     4 RLREMRCELSFLKNADGSACFSQGATCIWASCSGPGDVHASKASDEAMTLDISYRANCGDNKF-- 66

  Fly    78 RIREAAIRDVLELALLSEAHPRSKMSVQIQELEDRGSIDACAVNCACLAMLIGGLPLKYSFAAVH 142
            .:....|...|..|:..|..|.:.:||.:..::|.||:.|.|:|.||.|:|..|:|.:..|..|
Worm    67 NVLNNIIHSTLSNAINLELFPHTTISVTVHGIQDDGSMGAVAINGACFALLDNGMPFETVFCGV- 130

  Fly   143 AIINEQGEYVLDPDQSETLHQRASFT-----------------FAFDSVEGNLLLIQTKGSFKIA 190
            .|:..:.|.::||    |..|.|:.|                 .|.|:: |:...||.:.::.:|
Worm   131 LIVRVKDELIIDP----TAKQEAASTGRVLFSVCKGSDGHPEVCAMDAI-GHWDFIQLEAAWSLA 190

  Fly   191 QFNDIECLCLAASAEIFQFYR 211
            |         .:::.||.||:
Worm   191 Q---------PSASAIFDFYK 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rrp46	NP_650001.2	Rph	10..215	CDD:223761	62/216 (29%)
Rrp46	NP_650001.2	RNase_PH_RRP46	14..211	CDD:206777	61/213 (29%)
crn-5	NP_496284.1	RNase_PH_RRP46	5..202	CDD:206777	61/213 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162496
Domainoid	1	1.000	71	1.000	Domainoid score	I6219
eggNOG	1	0.900	-	-		E1_COG0689
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5981
Inparanoid	1	1.050	82	1.000	Inparanoid score	I3768
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53663
OrthoDB	1	1.010	-	-		D1129417at2759
OrthoFinder	1	1.000	-	-		FOG0004463
OrthoInspector	1	1.000	-	-		oto18241
orthoMCL	1	0.900	-	-		OOG6_103234
Panther	1	1.100	-	-	LDO	PTHR11953
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1221
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.800