Protein Alignment Irp-1B and ybhJ

DIOPT Version :10

• Sequence 1: NP_524303.2
• Gene: Irp-1B / 41269
• FlyBaseID: FBgn0024957
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_415292.2
• Gene: ybhJ / 945380
• ECOCYCID: G6401
• Length: 753
• Species: Escherichia coli
• Alignment Length: 774
• Identity: 179/774 - (23%)
• Similarity: 282/774 - (36%)
• Gaps: 200/774 - (25%)

  Fly   172 LIVPPGSGIVHQVNLEYLARVVFENDATDGSKILYPDSVVGTDSHTTMINGLGVLGWGVGGIEAE 236
            :.|||...::||...|.:|         .|.|:     ::|:||| |....||.:..|.||.|..
E. coli   121 IFVPPHIAVIHQYMREMMA---------GGGKM-----ILGSDSH-TRYGALGTMAVGEGGGELV 170

  Fly   237 AVMLGQSISMLLPEVIGYKLEGKLSPLVTSTDLVLTITKHLRQLGVV-GKFVEFYGPGVAELSIA 300
            ..:|..:..:..|.|:...|.||.:|.|...|:.|.|...:.:.|.| .|.:||.||||:.||..
E. coli   171 KQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVKNKVMEFVGPGVSALSTD 235

  Fly   301 DRATISNMCPEYGATVGYFPIDENTLGYMKQTNRSEKKIDIIRQYLKATQQLRNYADAAQDPKFT 365
            .|.::..|..|.......:..||....::....|.:       .|.:...|...|.|..
E. coli   236 FRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQ-------DYCQLNPQPMAYYDGC------ 287

  Fly   366 QSITLDLSTVVTSVSGPKRPHDRVSVSDMPEDFKSCLSSPVGFKGFAIAPEAQSAFGEFQWDDGK 430
              |::|||.:...::.|..|.:...:..:.::....|..        |..|::..      ..||
E. coli   288 --ISVDLSAIKPMIALPFHPSNVYEIDTLNQNLTDILRE--------IEIESERV------AHGK 336

  Fly   431 TY-----KLHHGSVVI--AAITSCTNTSNPSVMLGAGLL-AKKAVEKGLSILPYIKTSLSPGSGV 487
            ..     |:.:|.:.:  ..|..|:..:..:|:..|..| .:.......|:..|      |.|..
E. coli   337 AKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVY------PSSQP 395

  Fly   488 VTYYLKESGVIPYLEKLGFDIVGYG-------CMTCIGNSGPLEENVVNTIEKNGLVCAGVLSGN 545
            |...|.:.||:.       |::|.|       |..|.|..        :|...|||   .:....
E. coli   396 VFMDLAKKGVVA-------DLIGAGAIIRTAFCGPCFGAG--------DTPINNGL---SIRHTT 442

  Fly   546 RNFEGRIHPNTRANYLASPLLVIAYAIAGRVDIDFEKEPLGVDANG---KNVFLQDIWPTRSE-- 605
            |||..|.........:::..|:.|.:||...            |||   .:....|.|....|
E. coli   443 RNFPNREGSKPANGQMSAVALMDARSIAATA------------ANGGYLTSASELDCWDNVPEYA 495

  Fly   606 --IQEVENKHVIPAMFQEVYSKIELGSQDWQTLQVSEGKLFSWSADSTYIKRPPFFEGMTRDLPK 668
              :...:|:         ||.....|:                      .::|..:....:|.|:
E. coli   496 FDVTPYKNR---------VYQGFVKGA----------------------TQQPLIYGPNIKDWPE 529

  Fly   669 L----QSIQKARCLLFLGDSVTTDHISPAG--SIARTSPAARFLSERNITPRDFNSYGSRRGNDA 727
            |    .:|....|...|.:..|||.:.|:|  |..|::|..  |:|..::.|| ..|.||
E. coli   530 LGALTDNIVLKVCSKILDEVTTTDELIPSGETSSYRSNPIG--LAEFTLSRRD-PGYVSR----- 586

  Fly   728 IMSRGT--FANIRLVNKLVEKTG--PRTVHIPSQEELDIFDAAERYREEGTPLVLVVGK-----D 783
              |:.|  ..|.||...:.|.|.  .|...|..||.:|             ||...:|.     .
E. coli   587 --SKATAELENQRLAGNVSELTEVFARIKQIAGQEHID-------------PLQTEIGSMVYAVK 636

  Fly   784 YGSGSSRDWAAKGPFLLGVKAVIAESY-ERIHRSNLVGMGIIPLQFLPGQSAETLNLTGREVYNI 847
            .|.||:|:.||....::|..|.|||.| .:.:|||::..|::|||.....:.|    .|..:|
E. coli   637 PGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQMAEVPTFE----VGDYIY-- 695

  Fly   848 ALPESGLKPGQKIQVEADGTVFE-TILRFDTEV-DITYY------------KNGGILNY 892
                   .||.|..::..||.|: .::..|..| :||.|            |.|.::|:
E. coli   696 -------IPGIKAALDNPGTTFKGYVIHEDAPVTEITLYMESLTAEEREIIKAGSLINF 747

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irp-1B	NP_524303.2	PTZ00092	1..899	CDD:240263	179/774 (23%)
ybhJ	NP_415292.2	PRK11413	1..751	CDD:183125	179/774 (23%)