Protein Alignment Irp-1B and ireb2

DIOPT Version :10

• Sequence 1: NP_524303.2
• Gene: Irp-1B / 41269
• FlyBaseID: FBgn0024957
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: XP_005163029.2
• Gene: ireb2 / 652982
• ZFINID: ZDB-GENE-051205-1
• Length: 999
• Species: Danio rerio
• Alignment Length: 979
• Identity: 510/979 - (52%)
• Similarity: 677/979 - (69%)
• Gaps: 92/979 - (9%)

  Fly     1 MSGANPFAQFEKTF-SQAGTTYKYFDLASI-DSKYDQLPYSIRVLLESAVRNCDNFHILEKDVQS 63
            :...:|:.....|. |:.....|||....: |.:|::||:.:|||||||:|.||.|::..:||.|
Zfish    31 LQNEHPYGHLIDTLQSEQYQEQKYFSPQKLNDVRYEKLPFCMRVLLESAIRKCDEFYVKTEDVSS 95

  Fly    64 ILGWSPALKQGSNDVEVSFKPARVILQDFTGVPAVVDFAAMRDAVLDLGGDPEKINPICPADLVI 128
            ||.|.  ::|  |..||.|.||||:||||||:||:||.||||||:...|.||..:||.||.||::
Zfish    96 ILDWQ--VQQ--NQAEVVFSPARVLLQDFTGIPAMVDLAAMRDALAKQGVDPSLVNPRCPTDLIV 156

  Fly   129 DHSVQVDFARA------------------------------------------------------ 139
            |||:|:|:::.
Zfish   157 DHSLQIDYSKCGIQSPPASVDESPTVKSPAGRPSPRVSSSSGHCSGQRSGHRGGCSKPSCSDAPG 221

  Fly   140 ------------------------PDALAKNQSLEFERNKERFTFLKWGAKAFNNMLIVPPGSGI 180
                                    |:.:.:||.:|..|||||..|.||.:|:|||:.:|||....
Zfish   222 GRTAAVQIENTPLLCPFHLQPVSEPETMVRNQEMELIRNKERLQFFKWCSKSFNNVNVVPPDIST 286

  Fly   181 VHQVNLEYLARVVFENDATDGSKILYPDSVVGTDSHTTMINGLGVLGWGVGGIEAEAVMLGQSIS 245
            |||:|||||.:||.|.:.     .:|||||||||||||||||||:|||||||||:|||||||.:|
Zfish   287 VHQLNLEYLCKVVQEEEG-----FIYPDSVVGTDSHTTMINGLGILGWGVGGIESEAVMLGQPVS 346

  Fly   246 MLLPEVIGYKLEGKLSPLVTSTDLVLTITKHLRQLGVVGKFVEFYGPGVAELSIADRATISNMCP 310
            :.||:|:|.||.|.::||.||.|:||.|||||||.|:.||||||:||||.:||..||.||:||||
Zfish   347 LTLPQVVGCKLVGTINPLATSIDIVLGITKHLRQAGIGGKFVEFFGPGVPQLSAPDRTTIANMCP 411

  Fly   311 EYGATVGYFPIDENTLGYMKQTNRSEKKIDIIRQYLKATQQLRNYADAAQDPKFTQSITLDLSTV 375
            ||.|||.:||:|:.||.:.|.|..||:|:.::..||||.:..|:|.|.:::|::::.|.::||::
Zfish   412 EYNATVSFFPVDDITLQHFKHTICSEEKLLVLEDYLKAVKLFRSYDDQSEEPQYSEVIEMNLSSI 476

  Fly   376 VTSVSGPKRPHDRVSVSDMPEDFKSCLSSPVGFKGFAIAPEAQSAFGEFQWDDGKTYKLHHGSVV 440
            |..|||||||.|||:::.|.|||.|||:..||||||.|:.|.||....|: .||..|.|.|||||
Zfish   477 VPHVSGPKRPQDRVAITGMKEDFISCLNEKVGFKGFHISKEKQSTLVPFR-HDGAEYNLAHGSVV 540

  Fly   441 IAAITSCTNTSNPSVMLGAGLLAKKAVEKGLSILPYIKTSLSPGSGVVTYYLKESGVIPYLEKLG 505
            |||:.||||..||||||.||||||||||.||::.|||:|||.||||.||:||..|||:|:|:|||
Zfish   541 IAAVISCTNNCNPSVMLAAGLLAKKAVEAGLTVKPYIRTSLVPGSGTVTHYLNTSGVLPFLKKLG 605

  Fly   506 FDIVGYGCMTCIGNSGPLEENVVNTIEKNGLVCAGVLSGNRNFEGRIHPNTRANYLASPLLVIAY 570
            |::|||||.||:||:.||.|:||:.:::..||..|||||||:.|||:....||||||||.||:||
Zfish   606 FEVVGYGCATCVGNTAPLPESVVDAVKQGDLVACGVLSGNRHLEGRLCDCVRANYLASPPLVVAY 670

  Fly   571 AIAGRVDIDFEKEPLGVDANGKNVFLQDIWPTRSEIQEVENKHVIPAMFQEVYSKIELGSQDWQT 635
            ||||.|.|:.|.|||||:|:||:|||.|||||:.|:..:|...||.:||.|:.|::|.||..|..
Zfish   671 AIAGTVSINLETEPLGVNADGKDVFLCDIWPTKEEVNHIEENIVIASMFTELRSRMEKGSSFWNN 735

  Fly   636 LQVSEGKLFSWSADSTYIKRPPFFEGMTRDLPKLQSIQKARCLLFLGDSVTTDHISPAGSIARTS 700
            |:.:|..||.|...||||:.|.||..|::::...|||..|..||||||.||||||||||||||.|
Zfish   736 LESAESALFPWDPKSTYIRCPSFFSKMSKEVCSPQSIDGAYPLLFLGDKVTTDHISPAGSIARVS 800

  Fly   701 PAARFLSERNITPRDFNSYGSRRGNDAIMSRGTFANIRLVNKLVEKTGPRTVHIPSQEELDIFDA 765
            .||::|..:.:|||:|||||:||||||:|:|||||:|:|.|:|:.||||:|:|||:.:.||:|:|
Zfish   801 AAAKYLQSKRLTPREFNSYGARRGNDAVMTRGTFASIKLQNRLIGKTGPKTLHIPTGQTLDVFEA 865

  Fly   766 AERYREEGTPLVLVVGKDYGSGSSRDWAAKGPFLLGVKAVIAESYERIHRSNLVGMGIIPLQFLP 830
            ||||:.:|.||:::.||:||||||||||||||:||||:||||||:|:|||::||||||.||||||
Zfish   866 AERYQRDGVPLIILAGKEYGSGSSRDWAAKGPYLLGVRAVIAESFEKIHRNHLVGMGIAPLQFLP 930

  Fly   831 GQSAETLNLTGREVYNIALPESGLKPGQKIQVE-ADGTVFETILRFDTEVDITYYKNGGILNYMI 894
            ||:|::|.|.|:|.:.|.:||. |...|:|.|: :.|..|.....|:.::|:.::::||||.|:.
Zfish   931 GQNADSLELCGKERFTIDIPEE-LTARQQITVQTSTGKSFMVTALFENDMDVEFFRHGGILKYVA 994

  Fly   895 RKML 898
            |.:|
Zfish   995 RSLL 998

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irp-1B	NP_524303.2	PTZ00092	1..899	CDD:240263	510/979 (52%)
ireb2	XP_005163029.2	None