Protein Alignment Irp-1B and LOC1278105

DIOPT Version :10

• Sequence 1: NP_524303.2
• Gene: Irp-1B / 41269
• FlyBaseID: FBgn0024957
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: XP_061516346.1
• Gene: LOC1278105 / 1278105
• VectorBaseID: AGAMI1_003767
• Length: 787
• Species: Anopheles gambiae
• Alignment Length: 916
• Identity: 250/916 - (27%)
• Similarity: 379/916 - (41%)
• Gaps: 228/916 - (24%)

  Fly    31 SKYDQ---LPYSIRVLLESAVRNCD--------NFHILEKDVQSILGWSPALKQGSNDVE--VSF 82
            ||:||   |||      |...:|.:        ...:.||.:.|.|. .||    :.|:|  ||:
Mosquito    40 SKFDQNVYLPY------EKLQKNLEVVKKRLGRPLTLSEKVLYSHLD-DPA----NQDIERGVSY 93

  Fly    83 ---KPARVILQDFTGVPAVVDFAA---MRDAVLDLGGDPEKINPICPADLVIDHSVQV------D 135
               :|.||.:||.|...|::.|.:   .|.||              |:.:..||.::.      |
Mosquito    94 LRLRPDRVAMQDATAQMAMLQFISSGLKRVAV--------------PSTIHCDHLIEAQIGGEKD 144

  Fly   136 FARAPDALAKNQSLEFERNKERFTFL-----KWGAKAFNNMLIVPPGSGIVHQVNLEYLARVVFE 195
            .|||.|.           |.|.:.||     |:|...:.      |||||:||        ::.|
Mosquito   145 LARAKDI-----------NSEVYKFLSTAGAKYGVGFWK------PGSGIIHQ--------IILE 184

  Fly   196 NDATDGSKILYPDSVVGTDSHTTMINGLGVLGWGVGGIEAEAVMLGQSISMLLPEVIGYKLEGKL 260
            |.|..|  :|    ::||||||....|||.|..||||.:|..||......:..|.|||.||.||:
Mosquito   185 NYAFPG--LL----MIGTDSHTPNGGGLGGLCIGVGGADAVDVMANIPWELKCPNVIGVKLTGKI 243

  Fly   261 SPLVTSTDLVLTITKHLRQLGVVGKFVEFYGPGVAELSIADRATISNMCPEYGATVGYFPIDENT 325
            |...:..|::|.:...|...|..|..||:.|.||..:|....|||.||..|.|||...||.::..
Mosquito   244 SGWTSPKDVILKVADILTVKGGTGAIVEYMGNGVDSISCTGMATICNMGAEIGATTSIFPFNKRM 308

  Fly   326 LGYMKQTNRSEKKIDIIRQYLKATQQLRNYADAAQDPKFTQSITLDLSTVVTSVSGPKRPHDRVS 390
            ..|:..|.||....:       |.:...:...|....|:.|.|.::|.|:...::||..|.
Mosquito   309 ADYLASTGRSAIAAE-------AGKYQGSVLTADSGAKYDQVIEINLDTLEPHINGPFTPD---- 362

  Fly   391 VSDMPEDFKSCLSSPVGFKGFAIAPEAQSAFGEFQWDDGKTYKLHHGSVVIAAITSCTNTSNPSV 455
                       |:.|:...|      |.:....:..|           :.:..|.||||:|...
Mosquito   363 -----------LAHPISKLG------ANAKKNGYPMD-----------IRVGLIGSCTNSSYED- 398

  Fly   456 MLGAGLLAKKAVEKGL-SILPYIKTSLSPGSGVVTYYLKESGVIPYLEKLGFDIVGYGCMTCIGN 519
            |.....:||.|::.|| |.:|:   :::|||..:...::..|:....::.|..::...|..|||.
Mosquito   399 MGRCASIAKNAMKHGLKSKIPF---NVTPGSEQIRATIERDGIAKTFKEFGGTVLANACGPCIGQ 460

  Fly   520 SGPLEENVVNTIEKNGLVCAGVLSGNRNFEGRIHPNTRAN-YLASPLLVIAYAIAGRVDIDFEKE 583
               .:...|...|||.:    |.|.||||.||...|...: ::.||.||.|.:|||.::.:...:
Mosquito   461 ---WDRKDVKKGEKNTI----VTSYNRNFTGRNDANPATHCFVTSPELVTALSIAGTLNFNPLTD 518

  Fly   584 PLGVDANGKNVFLQDIWPTRSEIQEVENKHVIPAMFQEVYS---------KIELGSQDWQTLQVS 639
            .| ..|:||...|...:.     .|:..|...|.|  :.|.         |:::..:. |.||:.
Mosquito   519 EL-TGADGKKFKLDSPYG-----DELPQKGFDPGM--DTYEAPPSDGTSVKVDVDPKS-QRLQLL 574

  Fly   640 EGKLFSWSADSTYIKRPPFFEGMTRDLPKLQSI--QKARCLLFLGDSVTTDHISPAGSIARTSPA 702
            |                ||.....:||.::..:  .|.:|        ||||||.||      |.
Mosquito   575 E----------------PFDVWNGKDLTEMTVLIKVKGKC--------TTDHISAAG------PW 609

  Fly   703 ARFLSE-RNITPRDFNSYGSRRGNDAIMSRGTFANIRLVNKLVEKTGPRTVHIPSQEELDIFDAA 766
            .::... .||:...|....:...|:             :||:..:.......:|        |.|
Mosquito   610 LKYRGHLDNISNNMFIGATNIENNE-------------MNKIKNQVTGEWAGVP--------DVA 653

  Fly   767 ERYREEGTPLVLVVGKDYGSGSSRDWAAKGPFLLGVKAVIAESYERIHRSNLVGMGIIPLQFL-P 830
            ..|:.:|...|.|..::||.||||:.||..|..||.:|:|.:|:.|||.:||...|::||.|. |
Mosquito   654 RFYKSKGINWVAVGDENYGEGSSREHAALEPRHLGARAIITKSFARIHETNLKKQGLLPLTFANP 718

  Fly   831 G-----QSAETLNLTGREVYNIALPESGLKPGQKI--QVEADGTVFETILRFD-TEVDITYYKNG 887
            .     |....:::.|  :.|.|       ||:::  :::.||.|.:..|... .:..|.::|.|
Mosquito   719 ADYDKVQPTSKISILG--LNNFA-------PGKQLDCEIKTDGKVHKIKLNHSFNQQQIEWFKAG 774

  Fly   888 GILNYM 893
            ..||.|
Mosquito   775 SALNRM 780

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irp-1B	NP_524303.2	PTZ00092	1..899	CDD:240263	250/916 (27%)
LOC1278105	XP_061516346.1	None