Protein Alignment Irp-1B and aco1

DIOPT Version :10

• Sequence 1: NP_524303.2
• Gene: Irp-1B / 41269
• FlyBaseID: FBgn0024957
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: XP_012812984.1
• Gene: aco1 / 100216202
• XenbaseID: XB-GENE-1012108
• Length: 917
• Species: Xenopus tropicalis
• Alignment Length: 898
• Identity: 600/898 - (66%)
• Similarity: 721/898 - (80%)
• Gaps: 14/898 - (1%)

  Fly     4 ANPFAQFEKTFSQAGTTYKYFDLASI-DSKYDQLPYSIRVLLESAVRNCDNFHILEKDVQSILGW 67
            :|||....:....|....|:::|..: ||:|.:||:|||||||:|:||||.|.:.::||::||.|
 Frog    26 SNPFQHLAEPLDPAQQDKKFYNLNKLGDSRYARLPFSIRVLLEAAIRNCDEFLVKKQDVENILNW 90

  Fly    68 SPALKQGSNDVEVSFKPARVILQDFTGVPAVVDFAAMRDAVLDLGGDPEKINPICPADLVIDHSV 132
            .  |.|..| |||.|:|||||||||||||||||||||||||..|||||:.|||:||.|||||||:
 Frog    91 K--LTQHDN-VEVPFRPARVILQDFTGVPAVVDFAAMRDAVKRLGGDPQTINPVCPVDLVIDHSI 152

  Fly   133 QVDFARAPDALAKNQSLEFERNKERFTFLKWGAKAFNNMLIVPPGSGIVHQVNLEYLARVVFEND 197
            ||||.|..|:|.|||.||||||:|||.|||||::||.||.|:||||||:|||||||||||||:.|
 Frog   153 QVDFNRRSDSLQKNQELEFERNRERFEFLKWGSQAFQNMRIIPPGSGIIHQVNLEYLARVVFDQD 217

  Fly   198 ATDGSKILYPDSVVGTDSHTTMINGLGVLGWGVGGIEAEAVMLGQSISMLLPEVIGYKLEGKLSP 262
            .     ..||||:||||||||||:|||||||||||||||||||||.|||:|||||||||.|...|
 Frog   218 G-----YYYPDSLVGTDSHTTMIDGLGVLGWGVGGIEAEAVMLGQPISMVLPEVIGYKLMGNPHP 277

  Fly   263 LVTSTDLVLTITKHLRQLGVVGKFVEFYGPGVAELSIADRATISNMCPEYGATVGYFPIDENTLG 327
            ||||||:|||:||||||:|||||||||:|.|||:|||||||||:|||||||||..:||:|..::.
 Frog   278 LVTSTDIVLTVTKHLRQVGVVGKFVEFFGTGVAQLSIADRATIANMCPEYGATAAFFPVDLVSVQ 342

  Fly   328 YMKQTNRSEKKIDIIRQYLKATQQLRNYADAAQDPKFTQSITLDLSTVVTSVSGPKRPHDRVSVS 392
            |::||.|:|:|:..|::||:|....|::.:..|||.|:|.:.|||||||...||||||.|:||||
 Frog   343 YLQQTGRAEEKVQYIQKYLEAAGLFRDFNNTNQDPDFSQVVELDLSTVVPCCSGPKRPQDKVSVS 407

  Fly   393 DMPEDFKSCLSSPVGFKGFAIAPEAQSAFGEFQWDDGKT-YKLHHGSVVIAAITSCTNTSNPSVM 456
            :|..||::||.:..|||||.| |:... :.:.::....| |:|.|||||||||||||||||||||
 Frog   408 EMKSDFQNCLGAKQGFKGFQI-PQGHH-YDKVKFPYNNTEYELSHGSVVIAAITSCTNTSNPSVM 470

  Fly   457 LGAGLLAKKAVEKGLSILPYIKTSLSPGSGVVTYYLKESGVIPYLEKLGFDIVGYGCMTCIGNSG 521
            ||||||||||||.||.:.|||||||||||||||:||::|||.|||.|||||:|||||||||||||
 Frog   471 LGAGLLAKKAVEAGLCVKPYIKTSLSPGSGVVTFYLRDSGVQPYLSKLGFDVVGYGCMTCIGNSG 535

  Fly   522 PLEENVVNTIEKNGLVCAGVLSGNRNFEGRIHPNTRANYLASPLLVIAYAIAGRVDIDFEKEPLG 586
            ||.:.||..|.:..||..||||||||||||:||||||||||||.|||||||||.:.|||||:|||
 Frog   536 PLPDPVVEAITQGDLVAVGVLSGNRNFEGRVHPNTRANYLASPPLVIAYAIAGTIRIDFEKDPLG 600

  Fly   587 VDANGKNVFLQDIWPTRSEIQEVENKHVIPAMFQEVYSKIELGSQDWQTLQVSEGKLFSWSADST 651
            |:|.||.::|:||||||.|||.||.::|||.||:|||.|||..::.|..|:....:|:.|...||
 Frog   601 VNAEGKEIYLRDIWPTRDEIQAVERQYVIPGMFKEVYEKIEKVNESWNDLKAPTDELYPWDPKST 665

  Fly   652 YIKRPPFFEGMTRDLPKLQSIQKARCLLFLGDSVTTDHISPAGSIARTSPAARFLSERNITPRDF 716
            |||.||||:.:|.:|...:||..|..||.||||||||||||||:|||.|||||:|..|.:|||:|
 Frog   666 YIKSPPFFDSLTMELQPPKSITDAYVLLNLGDSVTTDHISPAGNIARNSPAARYLVNRGLTPREF 730

  Fly   717 NSYGSRRGNDAIMSRGTFANIRLVNKLVEKTGPRTVHIPSQEELDIFDAAERYREEGTPLVLVVG 781
            |||||||||||:|:|||||||||.||.:.|..|.|::.||.|.||||||||||:.:|..|:|:.|
 Frog   731 NSYGSRRGNDAVMARGTFANIRLFNKFINKQSPSTIYFPSNETLDIFDAAERYQNDGHNLILLTG 795

  Fly   782 KDYGSGSSRDWAAKGPFLLGVKAVIAESYERIHRSNLVGMGIIPLQFLPGQSAETLNLTGREVYN 846
            |:||||||||||||||||.|:|||:|||||||||||||||||||||:|||:|||.|.|:|:|.|.
 Frog   796 KEYGSGSSRDWAAKGPFLQGIKAVLAESYERIHRSNLVGMGIIPLQYLPGESAEALGLSGQERYT 860

  Fly   847 IALP-ESGLKPGQKIQVEAD-GTVFETILRFDTEVDITYYKNGGILNYMIRKM 897
            |.:| |..|:||..::::.| |..||.|:||||:|::|||:||||||||||||
 Frog   861 IVIPEEKDLRPGMNVEIKLDTGKSFEAIMRFDTDVELTYYRNGGILNYMIRKM 913

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irp-1B	NP_524303.2	PTZ00092	1..899	CDD:240263	600/898 (67%)
aco1	XP_012812984.1	PTZ00092	26..916	CDD:240263	600/898 (67%)