Protein Alignment Rfx and Rfx8

DIOPT Version :9

• Sequence 1: NP_001247023.2
• Gene: Rfx / 41266
• FlyBaseID: FBgn0020379
• Length: 919
• Species: Drosophila melanogaster
• Sequence 2: NP_001139132.1
• Gene: Rfx8 / 619289
• MGIID: 3588206
• Length: 596
• Species: Mus musculus
• Alignment Length: 558
• Identity: 144/558 - (25%)
• Similarity: 233/558 - (41%)
• Gaps: 113/558 - (20%)

  Fly   374 ASPDSDQSALGSSNKIASATIKWLSRNYETADGVSLPRSTLYNHYMQHCSEHKLEPVNAASFGKL 438
            |.|.|..|.||....|    |:||..|:...:|.|:||..:|..|::.|.:.....||.|:||||
Mouse     4 AVPASPASGLGLHRGI----IQWLVDNFCICEGFSVPRCLMYEIYVETCGQSAQNQVNPATFGKL 64

  Fly   439 IRSVFSGLRTRRLGTRGNSKYHYYGIRIKPGS--------LLNSQAMDDKQMLAAGYGPSSDGTG 495
            :|.||..|.||||||||:::|||.||.||..|        ||..::.....::|.|..|....
Mouse    65 VRLVFPDLGTRRLGTRGSARYHYDGIYIKKSSFFYAHYCYLLGKKSCHSGNLIAFGKFPDYSN-- 127

  Fly   496 GPGSGPMVSVTSSTAGQLTGSNGLGGGHGQRHSNGTKKHTFKP-ETYEACIQYIGDGTSALPSFP 559
                   |.....|.              :.||...|.....| ..:..|
Mouse   128 -------VLQQEETC--------------ENHSPIKKDPMGSPVSPFRRC--------------- 156

  Fly   560 PI---ELNHSFNSELTLEDVDTFRGLYREHCESFLDAVLNLEFNTVEFLLRDFWRASDNNNLDEC 621
            |:   ||.:.::.:|.:...|.    |..:|...|..|.|.|...||.|:..||::...:.:
Mouse   157 PVWEQELANKYSCKLVVFLADE----YCNYCRDILQNVRNQELEKVEDLITSFWKSRQQDTV--- 214

  Fly   622 EEEKYLSKTKLYLLCHCAEVQKFVREVDYQFYQNTVDVIIPDVLRSIPNALTQAIRNFAKNLEIW 686
                        :|....:|::.:...|.|.|:...|:::||.|..:.....:::|.|:|..::|
Mouse   215 ------------MLMSLPDVRQLLGCYDMQLYKGLEDMLLPDFLEDVSIQYLKSVRLFSKRFKLW 267

  Fly   687 LCESMLGVPEQLAQIKTSAVSAFCQTLRRYTSLNHLAQAARAVLQNGAQISQMLSDLNRV----- 746
            |..::.|.|..|...|...|:.|.:.|||.|.|:::|:..:.||:|..:|..:.|||..:
Mouse   268 LLGALEGFPAILQISKLKEVTGFVKRLRRKTYLSNMAKTMKMVLKNSRRIGLLKSDLRAIIREGT 332

  Fly   747 -----------DFHNVQEQAAWVSQCAPAVVQRLESDFKAALQQQSSLEQWASWLQLVVESAMEE 800
                       ..|..:.::....:|...::..||:....|    ..|...:|.||::|   .:.
Mouse   333 LDISKKVLEGDSDHEEEPESHTEMKCLGCLISLLETSTDLA----ELLNCVSSNLQVLV---FQP 390

  Fly   801 YNGKPTYARAARQFLLKWSFYSSMIIRDLTLRSASSFGSFHLIRLLFDEYMFYLVEHKIAEAQDK 865
            ...|..:.:.|..|.|||:|..:.:.:.:||....|||::||..||..||:.:::|..|.|.::
Mouse   391 SKNKEDFIKLAASFQLKWNFLLTAVSKAMTLSHRDSFGAWHLFHLLLLEYVIHILESCIEEEEE- 454

  Fly   866 TAIAVICERMKKDMDFEFECQFAYITSDTEHQTTPSSA 903
                   |.:....|         :.||.:..|.|..|
Mouse   455 -------EDLGSLQD---------LLSDDQFLTQPDQA 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rfx	NP_001247023.2	RFX_DNA_binding	393..466	CDD:280427	35/72 (49%)
Rfx8	NP_001139132.1	RFX_DNA_binding	20..90	CDD:280427	33/69 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910