Protein Alignment Rfx and sak1

DIOPT Version :9

• Sequence 1: NP_001247023.2
• Gene: Rfx / 41266
• FlyBaseID: FBgn0020379
• Length: 919
• Species: Drosophila melanogaster
• Sequence 2: NP_594086.1
• Gene: sak1 / 2543421
• PomBaseID: SPAC3G9.14
• Length: 766
• Species: Schizosaccharomyces pombe
• Alignment Length: 711
• Identity: 153/711 - (21%)
• Similarity: 261/711 - (36%)
• Gaps: 205/711 - (28%)

  Fly   282 YLVPVEEGILLNGSAHSLSQSQSQSHGRDSPHSLTVSSRDWERDADRVNGTNRHWVQEVAYIQEA 346
            :::|.||..|...|..|.|     :|.|.|         |.|::.:         ::.:|...|.
pombe    33 FMLPQEENFLNRPSITSES-----AHPRGS---------DLEQETE---------LKRLALEHEH 74

  Fly   347 QSTPQTPTSTTTTHSASGGSLGTGGGGASPDSDQSALGSSNKIASATIKWLSRNYETADGVSLPR 411
            .|...........|.:           |:.:..:...|         |.||.|..|.....::.|
pombe    75 YSLESLAEKLRMDHVS-----------ANSEKFRQVFG---------ICWLKRACEEQQDAAVQR 119

  Fly   412 STLYNHYMQHCSEHKLEPVNAASFGKLIRSVFSGLRTRRLGTRGNSKYHYYGIRIK--------- 467
            :.:|.||::.|:...::|:|:||||||:|.:|..::|||||.||:|||||.||:::
pombe   120 NQIYAHYVEICNSLHIKPLNSASFGKLVRLLFPSIKTRRLGMRGHSKYHYCGIKLRGQDSFRRLR 184

  Fly   468 ----------------------------------------PGSLLNSQAMDDKQMLAAGYGPSSD 492
                                                    |.| :|:.|:..|..:.    ||||
pombe   185 TFSDSSLSPVSCSSFPKPIPNHFENDVSSIQNTNQRVESSPAS-VNAAAIVRKSAVT----PSSD 244

  Fly   493 GTGGPGSGPMVSVT---SSTAGQLTGSNGLGGGH------GQRHSNGTKKHTFKPE--------- 539
                |.:.|..|:.   |.|..||..|......|      .|.:......|:..|.
pombe   245 ----PYNSPPPSIPLLGSQTNLQLAPSFAAPQAHPLPSHLSQSNVPPQLSHSSVPSPAPPRSVSQ 305

  Fly   540 -TY------EACIQYIGDGTSALPSFPP------IELNHSFNSELTLE-------------DVDT 578
             ||      :....::...:|.:|:..|      ..|.||...:|.|:             ||.:
pombe   306 PTYFSQPMPQFSSSFVPGTSSIVPTLHPASAQEDFNLQHSLFFKLKLKFLPPHKLPWIPSLDVSS 370

  Fly   579 F----------------------RGLYREHCESFLDAVLNLEFNTVEFLLRDFWRASDNNNLDEC 621
            |                      ..:|..||.:.:::|..:...  :||       |:.:|....
pombe   371 FSLPPIDYYLNGPYDNVEAKSALMNIYSSHCITLIESVRYMHLK--QFL-------SEISNFPNS 426

  Fly   622 EEEKYLSKTKLYLLCHCAEVQKFVREVDYQFYQNTVDVIIPDVLRSIPNALTQAIRNFAKNLEIW 686
                 ||.:.|.|| ......|::...|...|:..:.::.|..|:.:|..:...:|:.|:||...
pombe   427 -----LSPSLLALL-SSPYFTKWIERSDTVMYREILKLLFPMTLQVVPPPVLVLLRHLAENLVNH 485

  Fly   687 LCESMLGVPEQLAQIKTSAVSAFCQTLRRYTSLNHLAQAARAVLQNGAQISQMLSD--------- 742
            :..........|.|:|:...:.|...|.|...:|..|.||...|.|.|....:.:|
pombe   486 ISSIYASHSSCLLQVKSETAAIFSNLLSRLLRVNDTAHAAARFLANPADRHLICNDWERFVSTRF 550

  Fly   743 -LNRVDFHNVQEQAA----W---VSQCA-PA-VVQRLESDFKAA--LQQQSSLEQWASWLQLVVE 795
             ::|....|.:|..|    |   :|.|: |: ::..|:...:|:  ...:..|.|....|..:.:
pombe   551 IVHRELMCNDKEAVAALDEWYSILSTCSNPSELLDPLKDKHEASDTSMNRVELRQIDGVLDRMAD 615

  Fly   796 SAMEEYNGKPTYARAARQFLLKWSFYSSMIIRDLTLRSASSFGSFHLIRLLFDEYMFYLVE 856
            ..:|..:..|:.  :.|.|||......:.::|::|:....:||:..:||...||||.::.|
pombe   616 FFLELPSRFPSC--SPRMFLLCLGALQTSVLREITVSGGEAFGALWVIRCWVDEYMTWVAE 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rfx	NP_001247023.2	RFX_DNA_binding	393..466	CDD:280427	34/72 (47%)
sak1	NP_594086.1	RFX_DNA_binding	98..174	CDD:280427	35/84 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	81	1.000	Domainoid score	I2320
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	136	1.000	Inparanoid score	I1396
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000699
OrthoInspector	1	1.000	-	-		oto101820
orthoMCL	1	0.900	-	-		OOG6_102578
Panther	1	1.100	-	-	LDO	PTHR12619
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1282
SonicParanoid	1	1.000	-	-		X291
TreeFam	0	0.000	Not matched by this tool.
	10	9.990