Protein Alignment Rfx and rfx5

DIOPT Version :10

• Sequence 1: NP_001247023.2
• Gene: Rfx / 41266
• FlyBaseID: FBgn0020379
• Length: 919
• Species: Drosophila melanogaster
• Sequence 2: XP_068071336.1
• Gene: rfx5 / 101884332
• ZFINID: ZDB-GENE-070717-3
• Length: 590
• Species: Danio rerio
• Alignment Length: 551
• Identity: 112/551 - (20%)
• Similarity: 190/551 - (34%)
• Gaps: 190/551 - (34%)

  Fly   374 ASPDSDQSALGSSNKIASA----TIKWLSRNYETADGVSLPRSTLYNHYMQHCSEHKLEPVNAAS 434
            :.|.:.:.: |.||.:.:|    |..|:..:.|......||:..:|..|.:||...:..|::||:
Zfish    62 SGPSAGEKS-GDSNSVNTADQLHTCNWIRSHLEEHPDTCLPKQDVYETYRKHCDNLQHRPLSAAN 125

  Fly   435 FGKLIRSVFSGLRTRRLGTRGNSKYHYYGIRIKPGSLLNSQAMDDKQMLAAGYGPSSDGTGGPGS 499
            |||:||.:|..::.||||.||.|||.|.|||.|  ::||...:           |:.|....|
Zfish   126 FGKIIRDIFPNIKARRLGGRGQSKYCYSGIRRK--TVLNMPLL-----------PNLDLKNDP-- 175

  Fly   500 GPMVSVTSSTAGQLTGSNGLGGGHGQRHSNGTKKHTFKPETYEACIQYIGDGTSALPSFPPIELN 564
                       .:||                ....|:|.|..||..:.|.|....:       |.
Zfish   176 -----------SELT----------------ELVQTYKQEVTEAACELICDWAQKI-------LK 206

  Fly   565 HSFNSELTLEDVDTFRGLYREHCESFLDAVLNLEFNTVEF---------------LLRDFWRAS- 613
            .||::.     |:..|.|.:||       ::|...:..|.               :::....||
Zfish   207 RSFDTV-----VEIARFLVQEH-------IVNPRCSQAELVTSAALAGGPSKPHKVIKKIPAASR 259

  Fly   614 ------DNNNLDECEEEK-----------YLSK---TKLYLLCHCAEVQKFVREVDYQFYQNT-- 656
                  |..:::..::||           .:|:   .|:    ..|.|:.:::::.....:.|
Zfish   260 AGGAEEDGGSVENKQKEKDGVEQPPSNKQQVSEKPPNKV----ESARVEAYMKKLPQLLPRGTVP 320

  Fly   657 ---------------VDVIIPDVLRSIPN---------------ALTQAIRNFAKNLEIWLCESM 691
                           |.|.:|..:.:||:               :|:...|   :...:.:..|.
Zfish   321 EKTSPPCLAPADSGSVQVTLPITVTTIPSQPGGTVPVMILPSGVSLSYPER---EKTSVTVATSA 382

  Fly   692 LGVP---------EQLAQIKTSAVSAFCQTLRRYTS----------LNHL----------AQAAR 727
            ...|         .:.|...:::|||....|:|...          |:||          |...|
Zfish   383 APTPVVQRARPAAPKRAPDPSTSVSASGVVLKRKRGRPRKQRPEDLLSHLQSPSIPTPNPALLTR 447

  Fly   728 AVLQNGA------------------QISQMLSDLNRVDFHNVQEQAAWVSQCAPAVVQRLESDFK 774
            .|:|...                  |.|.|||.|..:...:..|..:.|.||.||  ...|....
Zfish   448 GVIQKAMPSCPPAAPSQLVEIVIQDQQSLMLSQLPTIQEVSDVEHRSVVVQCHPA--PEAEKQQS 510

  Fly   775 AALQQQSSLEQWASWLQLVVESAMEEYNGKP 805
            ..|.|..:...:....::|::.|.....|:|
Zfish   511 VLLMQGPNQLNYEQGRRMVIQRAPLSSEGRP 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rfx	NP_001247023.2	RFX_DNA_binding	392..468	CDD:460512	32/79 (41%)
rfx5	XP_068071336.1	RFX5_N	20..78	CDD:375753	4/16 (25%)
		RFX_DNA_binding	81..159	CDD:460512	32/79 (41%)
		PHA03247	<238..466	CDD:223021	32/234 (14%)