Protein Alignment Rfx and rfx1

DIOPT Version :9

• Sequence 1: NP_001247023.2
• Gene: Rfx / 41266
• FlyBaseID: FBgn0020379
• Length: 919
• Species: Drosophila melanogaster
• Sequence 2: XP_031755324.1
• Gene: rfx1 / 100491798
• XenbaseID: XB-GENE-994757
• Length: 880
• Species: Xenopus tropicalis
• Alignment Length: 961
• Identity: 374/961 - (38%)
• Similarity: 501/961 - (52%)
• Gaps: 171/961 - (17%)

  Fly     3 TRLAPQRQFILS---TRSAIVDATSPPEDSAEEQQQLTV--------EVESATNGVITNSTTSPP 56
            |:..|| |::..   |.|....|:.....||::...:||        :.|.:..|..|.:|..|.
 Frog    18 TQGTPQ-QYVAELQVTPSGSSQASGAQTPSAQQYIVVTVSEGSVRGSDGELSPGGTPTPTTGVPT 81

  Fly    57 PHAEQFEFCTEDGVVVSATLEDVMTQVKLFPL-LQNCQLLQKKLVDEDDDSTGVGATDADQLEVI 120
            ...:|.: ..:..::|.|.::..:|.|.  || |....:.|::||.:....    .|.|.|:.:.
 Frog    82 QVVQQVQ-AAQQRLLVQARVQPKVTAVS--PLQLAGSSVPQQRLVVQSSPQ----GTKAAQVSLT 139

  Fly   121 SVVLPMDAEDSTSDAHLHGHVVNSSSDTMGTITTTEPNGTTVTHSI---------PIHSMADLAA 176
            ...:......|..|.       :|.|...|.....:.:||....|:         |:|.:.
 Frog   140 VHTVQQQPAHSPPDG-------DSPSLKAGQAQPLQLHGTQQERSVVQANPQKSSPVHQLT---- 193

  Fly   177 IKDGVDLAQQVANGQVTVVQTTEDDDGTPFITVTVSGQEQNYQVQYVD-SELYHSNSSQTQMTYP 240
                |...|.| .|...|.|..:    .|...|..|      |||||: ::..::.|:....:||
 Frog   194 ----VQALQHV-QGAAEVQQLQQ----VPVQHVYPS------QVQYVEGTDATYTGSTIRSGSYP 243

  Fly   241 FCPVGDY-QGNGQTAYYSTTGQYGTTSSAGGSSNGAHSTTLPYLVPVEEGILLNGSAHSLSQSQS 304
            :.....| |..|.| ||...|..|..||...|...|.|.::|
 Frog   244 YTETPLYTQATGST-YYEAQGATGQVSSPTSSPALASSPSVP----------------------- 284

  Fly   305 QSHGRDSPHSLTVSSRDWERDADRVNGTNRHWVQEVAYIQEAQSTPQTPTSTTTTHSASGGSLGT 369
                                                .|:...|      ..|.||.||:.|  ||
 Frog   285 ------------------------------------MYVSGGQ------ILTNTTQSAASG--GT 305

  Fly   370 GGGGASPDSDQSA------LGSS-------NKIASATIKWLSRNYETADGVSLPRSTLYNHYMQH 421
            ||||:...:....      :|||       .:.:.||::||..|||||:||||||||||.||:.|
 Frog   306 GGGGSGSGTGTYVIQGGFIMGSSTQSYSHTTRASPATVQWLLDNYETAEGVSLPRSTLYCHYLLH 370

  Fly   422 CSEHKLEPVNAASFGKLIRSVFSGLRTRRLGTRGNSKYHYYGIRIKPGSLLNSQAMDDKQMLAAG 486
            |.|.||||||||||||||||||.|||||||||||||||||||:|||..|.| .:.|:|:|.||..
 Frog   371 CQEQKLEPVNAASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGLRIKASSPL-LRLMEDQQHLAMR 434

  Fly   487 YGPSSDGTGGPGSGPMVSVTSSTAGQLTG-SNGLGGGHGQRHSNGTKKHTFKPETYEACIQYIGD 550
            ..|.|.           .....|..::.| |||:||  .|:.::|....:.:.:.|:   |:: |
 Frog   435 QQPFSQ-----------KQRLKTVQKMEGMSNGVGG--SQQQASGLSDISAQVQQYQ---QFL-D 482

  Fly   551 GTSALPSFPPIEL-NHSFNSELTLEDVDTFRGLYREHCESFLDAVLNLEFNTVEFLLRDFWRASD 614
            .:..||.|..::| .......:||.:|..|:.|||||||:.:|.|:||:|..||.|.:.|||.:.
 Frog   483 ASKTLPEFAEMDLQGKPLPDGVTLANVKAFQLLYREHCEAIVDVVVNLQFTLVETLWKTFWRFNQ 547

  Fly   615 NNNLD---ECEEEKYLSKTKLYLLCHCAEVQKFVREVDYQFYQNTVDVIIPDVLRSIPNALTQAI 676
            ..:.|   :.|.||.|.|..|.||.....:.|:.|:.|:..||..|:.:||||||.||:||||||
 Frog   548 TQHSDSTIDDEAEKRLPKDCLVLLSKYEPLLKWSRDCDHLLYQVLVETLIPDVLRPIPSALTQAI 612

  Fly   677 RNFAKNLEIWLCESMLGVPEQLAQIKTSAVSAFCQTLRRYTSLNHLAQAARAVLQNGAQISQMLS 741
            |||||:||.||..:|:.:||::.::|.||.|||.||||||||||||||||||||||.|||:||||
 Frog   613 RNFAKSLESWLTSAMMNIPEEMVRVKASAASAFAQTLRRYTSLNHLAQAARAVLQNTAQINQMLS 677

  Fly   742 DLNRVDFHNVQEQAAWVSQCAPAVVQRLESDFKAALQQQSSLEQWASWLQLVVESAMEEYNGKPT 806
            |||||||.||||||:||.:||..||||||.|||..|||||||||||.||..||...::.|.|.|.
 Frog   678 DLNRVDFTNVQEQASWVCRCADRVVQRLEQDFKLTLQQQSSLEQWAEWLDSVVSQVLKPYQGSPG 742

  Fly   807 YARAARQFLLKWSFYSSMIIRDLTLRSASSFGSFHLIRLLFDEYMFYLVEHKIAEAQDKTAIAVI 871
            :.:||:.|||||||||||:|||||||||:|||||||||||:||||:||:||::|:|:.:|.|||:
 Frog   743 FPKAAKLFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMYYLIEHRVAQARGETPIAVM 807

  Fly   872 CE---------RMKKDMDFEFECQFAYITSDTEHQTTPSSASSGGDVGNEA 913
            .|         .:.:|.:.|.| :......|..|....:.:...|.:|:::
 Frog   808 GEFANPGNALRTLDQDKEEEEE-EEDESDEDLTHDLPLTMSDPSGALGSDS 857

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rfx	NP_001247023.2	RFX_DNA_binding	393..466	CDD:280427	60/72 (83%)
rfx1	XP_031755324.1	RFX1_trans_act	152..301	CDD:398335	46/240 (19%)
		RFX_DNA_binding	340..415	CDD:396712	61/74 (82%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	389	1.000	Domainoid score	I786
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	529	1.000	Inparanoid score	I1199
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D278246at33208
OrthoFinder	1	1.000	-	-		FOG0000699
OrthoInspector	1	1.000	-	-		otm49147
Panther	1	1.100	-	-	O	PTHR12619
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X291
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160