DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jumu and foxc1b

DIOPT Version :9

Sequence 1:	NP_524302.1	Gene:	jumu / 41265	FlyBaseID:	FBgn0015396	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_571804.1	Gene:	foxc1b / 79375	ZFINID:	ZDB-GENE-010302-2	Length:	433	Species:	Danio rerio

Alignment Length:	225	Identity:	61/225 - (27%)
Similarity:	99/225 - (44%)	Gaps:	48/225 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   350 MQSNYSLGSPSSLSSSSASSPLGNVSNL---VNIANNNTSGAGSGLVKPLQQ-----KVKLP--- 403
            ||:.|.:         |:.||||.|..:   .......|.|..:|:..|:..     ..:.|
Zfish     1 MQARYPV---------SSQSPLGVVPYIPGDQGFYRTATGGGYTGMPAPMSMYSHATHEQYPGGM 56

  Fly   404 --------PVGSP--FPKPAYSYSCLIALALKNSRAGSLPVSEIYSFLCQHFPYFENAPSGWKNS 458
                    |...|  ..||.|||..||.:|::||....:.::.||.|:.:.||::.:...||:||
Zfish    57 ARAYGPYAPAQQPKDMVKPPYSYIALITMAIQNSSDKKITLNGIYQFIMERFPFYRDNKQGWQNS 121

  Fly   459 VRHNLSLNKCFEKIERPATNGNQRKGCRWAMNPDRINKMD-----EEVQKWSRKDPAAIRGAMVY 518
            :|||||||:||.|:  |..:....||..|.::||..|..:     ...:::.:||        |.
Zfish   122 IRHNLSLNECFVKV--PRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKD--------VL 176

  Fly   519 PQHLESLERGEMKHGSADSDVELDSQSEIE 548
            .:..:...:|:...|.|   .|.|:|..::
Zfish   177 REKEDRDRQGKDNPGQA---CEQDAQQPVK 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jumu	NP_524302.1	Forkhead	411..499	CDD:278670	36/92 (39%)
foxc1b	NP_571804.1	Forkhead	74..160	CDD:278670	36/87 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	174..250		8/41 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	318..355
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820