DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jumu and Foxj2

DIOPT Version :9

Sequence 1:	NP_524302.1	Gene:	jumu / 41265	FlyBaseID:	FBgn0015396	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_068699.1	Gene:	Foxj2 / 60611	MGIID:	1926805	Length:	565	Species:	Mus musculus

Alignment Length:	308	Identity:	80/308 - (25%)
Similarity:	118/308 - (38%)	Gaps:	82/308 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   411 KPAYSYSCLIALALKNSRAGSLPVSEIYSFLCQHFPYFENAPSGWKNSVRHNLSLNKCFEKIERP 475
            ||.|||:.||..|:.:|.|..:.:||||.::|.:|||::||..|||||:||||||||||.|:.||
Mouse    66 KPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFRKVPRP 130

  Fly   476 ATNGNQRKGCRWAMN--PD----RINKMDEEVQKWSRKDPAAIRGAMVYPQHLESLERGEMKHGS 534
              ..:..||..|.::  ||    |.:..|:::.:.|.:..|:           :|...|....|.
Mouse   131 --RDDPGKGSYWTIDTCPDISRKRRHPPDDDLSQDSPEQEAS-----------KSPRGGVPGSGE 182

  Fly   535 ADSDVELDSQSEIEESSDLEEHEFEDTMVDAMLVEEEDEEEDGDDDEQIINDFDAEDERHANGNQ 599
            |....|...|..::..|.:..:......||...|                          |.|..
Mouse   183 ASLSHEGTPQMSLQSPSSVANYSQGPGSVDGGAV--------------------------AAGAP 221

  Fly   600 ANNLPINHPLLGQKSNDFDIEVGDLYDAIDIEDDKESVRRII-------SNDQHIIELNPADLNA 657
            ........|.|...::||...    |..|:.:|...|.|.:.       |:.||.......|:..
Mouse   222 GQESTEGAPPLYNTNHDFKFS----YSEINFQDLSWSFRNLYKSMLERSSSSQHGFSSLLGDMPP 282

  Fly   658 TDGYNQQPALKRARVDINYAIGPAGELEQQYGQKVKVQQVIQPQQHPP 705
            ::.|                          |..:.:.||...||..||
Mouse   283 SNNY--------------------------YVYQQQQQQQPPPQPQPP 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jumu	NP_524302.1	Forkhead	411..499	CDD:278670	44/93 (47%)
Foxj2	NP_068699.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	29..61
		Forkhead	66..143	CDD:278670	41/78 (53%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	125..233		25/146 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	290..399		6/15 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	543..565
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820