DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jumu and foxh1

DIOPT Version :9

Sequence 1:	NP_524302.1	Gene:	jumu / 41265	FlyBaseID:	FBgn0015396	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_571577.1	Gene:	foxh1 / 57930	ZFINID:	ZDB-GENE-000616-15	Length:	472	Species:	Danio rerio

Alignment Length:	199	Identity:	55/199 - (27%)
Similarity:	83/199 - (41%)	Gaps:	52/199 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   338 SIASAANSPHH-QMQSNYSLGSPSSLSSSSASSPL----GNVSNLVNIANNN------------- 384
            ::...|...|| ..:..|   |.|..|...:|:||    |.:.....:|.::
Zfish    17 TVGEGAQRDHHLDCRIGY---SSSKRSCHRSSNPLLELGGRLDKSTGMAQDSCYRAKATNQGPWE 78

  Fly   385 -TSGAGSGLVKPLQQKVKLPPVGSPFPKPAYSYSCLIALALKNSRAGSLPVSEIYSFLCQHFPYF 448
             ..|..||..|...|:         :|||.|||..:||:.::||....|.:|||...:...||:|
Zfish    79 LQDGNSSGGKKKNYQR---------YPKPPYSYLAMIAMVIQNSPEKKLTLSEILKEISTLFPFF 134

  Fly   449 ENAPSGWKNSVRHNLSLNKCFEKI----ERPATNGNQRKGCRWAMNPDRI------------NKM 497
            :....||::|||||||...||.|:    .:|     |.||..|.:..:||            ::.
Zfish   135 KGNYKGWRDSVRHNLSSYDCFVKVLKDPGKP-----QGKGNFWTVEVNRIPLELLKRQNTAVSRQ 194

  Fly   498 DEEV 501
            ||.:
Zfish   195 DETI 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jumu	NP_524302.1	Forkhead	411..499	CDD:278670	35/103 (34%)
foxh1	NP_571577.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	36..56		6/19 (32%)
		FH	97..174	CDD:238016	33/81 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	211..246
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	261..360
		SMAD-interaction domain (SID)	339..465
		Fast/FoxH1 motif 1 (FM1)	357..361
		Fast/FoxH1 motif 2 (FM2)	367..373
		SMAD interaction motif (SIM)	428..448
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820