DRSC/TRiP Functional Genomics Resources

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Protein Alignment jumu and foxh1

DIOPT Version :9

Sequence 1:NP_524302.1 Gene:jumu / 41265 FlyBaseID:FBgn0015396 Length:719 Species:Drosophila melanogaster
Sequence 2:NP_001017084.1 Gene:foxh1 / 549838 XenbaseID:XB-GENE-1194372 Length:515 Species:Xenopus tropicalis


Alignment Length:489 Identity:101/489 - (20%)
Similarity:160/489 - (32%) Gaps:175/489 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   278 IKLAPGIGGLTFANSAAYQKLKQ--TSLVKSPGGISPGAGSNMGLKREDSNKRGLQASTTPKSIA 340
            :..|||         .:|::..|  ..|.:..|..||..||          ..||...|...|..
 Frog    36 VPAAPG---------HSYEQCAQPWPPLYREGGTWSPDRGS----------MHGLSPGTQEGSCT 81

  Fly   341 SAANSPHHQMQSNYSLGSPSSLSSSSASSPLGNVSNLVNIANNNTSGAGSGLVKPLQQKVKLPPV 405
            .|..:..       |||...:||..|.......                                
 Frog    82 QAEGTKD-------SLGGDETLSRKSKKKNYHR-------------------------------- 107

  Fly   406 GSPFPKPAYSYSCLIALALKNSRAGSLPVSEIYSFLCQHFPYFENAPSGWKNSVRHNLSLNKCFE 470
               :.||.|||..:|||.::||....|.:|:|...:...||:|:....|||:|:|||||.|.||:
 Frog   108 ---YAKPPYSYLAMIALVIQNSPEKRLKLSQILKEVSTLFPFFKGDYMGWKDSIRHNLSSNDCFK 169

  Fly   471 KI----ERPATNGNQRKGCRWAMNPDRINKMDEEVQKWSRKDPAAIRGAMVY------------- 518
            |:    .:|     |.||..|.::..||     .:.....::.|..||...|             
 Frog   170 KVLKDPGKP-----QAKGNFWTVDVSRI-----PLDAMKLQNTALTRGGSDYFVQDLAPYILHNY 224

  Fly   519 --------------PQHLESLERGEMKHGSADSDVELDSQSEIEESSDLEEHEFEDTMVDAMLVE 569
                          |.|..||...|..|       :.::..::..|          .|:|::|.:
 Frog   225 KYEHNVVVYAPHHMPSHASSLPLAEDPH-------QTNTGGKLNTS----------FMIDSLLND 272

  Fly   570 EEDEEEDGDDDEQIINDF--DAEDERHANGNQANNLPINHPLLGQKSNDFDIEVGDLYDAIDIED 632
            .:|.:         :.|.  :.|.:|.:.....||:..:.|||..:|.......|..:.|     
 Frog   273 LQDVD---------LPDVPRNIESQRISPAVAINNMWSSAPLLYPQSKPTRNGRGPGFSA----- 323

  Fly   633 DKESVRRIISNDQHIIELNPADLNATDGYNQQPALKRARVDINYAIGPAGELEQQYGQKVKVQQV 697
               |.....|:...|..::|.....|...::         |:      .|...|:.|...|    
 Frog   324 ---SHSTYSSSSSSISTISPVGFQETQERSE---------DL------LGRQTQRLGFPTK---- 366

  Fly   698 IQPQQ---------------HPPTYNRRKMPLVN 716
             :|::               :.||...:||||::
 Frog   367 -RPREDDGCSTPSSDTDAGNYSPTEPPKKMPLLS 399

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
jumuNP_524302.1 Forkhead 411..499 CDD:278670 36/91 (40%)
foxh1NP_001017084.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 55..103 16/64 (25%)
FH 110..188 CDD:238016 34/82 (41%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 307..399 20/119 (17%)
SMAD-interaction domain (SID) 377..503 6/23 (26%)
Fast/FoxH1 motif 1 (FM1). /evidence=ECO:0000255 402..406
Fast/FoxH1 motif 2 (FM2). /evidence=ECO:0000255 412..418
SMAD-interaction motif (SIM) 467..488
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1270467at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.920

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