DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment jumu and foxj1

DIOPT Version :9

Sequence 1:	NP_524302.1	Gene:	jumu / 41265	FlyBaseID:	FBgn0015396	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	XP_012827170.1	Gene:	foxj1 / 496834	XenbaseID:	XB-GENE-853648	Length:	512	Species:	Xenopus tropicalis

Alignment Length:	599	Identity:	138/599 - (23%)
Similarity:	218/599 - (36%)	Gaps:	183/599 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 VMPLINSTSAGMFSPKKNKTASSTQGRSGAVPSSPSAERDQHKSHLTFSPAQMKVSAGSMRRDQV 197
            :||  .|...|:...:..:..:.....|.|..::.:|.|       ||.|:...:.. ::.::|.
Frog    13 LMP--GSRVRGVNRKRAGRAITHLPTTSAAAAAAAAASR-------TFLPSSALLGP-TVPQEQF 67

  Fly   198 MAHIPKQISVVTGTGTTAPATMATNSV-LQRRNSSAVDAVRKDLVTELRKAQSSPVPNSLEELGK 261
            :.|   |..::....|.||..|..:.| .|.......|:.          :.|..:.:||..|..
Frog    68 LDH---QALLMFDLPTVAPIDMEDSWVTFQAEGEQGQDSF----------SSSVNLDDSLTSLQW 119

  Fly   262 GKGSTLLNASVGATNTIKLAPGIGGLTFANSAAYQKLKQTSLVKSPGGISPGAGSNMGLKREDSN 326
            .:..::|||:||.      ||..|     :|..|:.|.....  ||....|..   :|:
Frog   120 LQEFSILNANVGK------APSSG-----DSHGYKHLSGAPC--SPLAADPAC---LGM------ 162

  Fly   327 KRGLQASTTPKSIASAANSPHHQMQSNYSLGSPSSLSSSSASSPLGNVSNLVNIANNNTSGAGSG 391
                               ||       :.|.|.| ||:|.:|.||
Frog   163 -------------------PH-------TPGKPIS-SSTSRASHLG------------------- 181

  Fly   392 LVKPLQQKVKLPPVGSPFPKPAYSYSCLIALALKNSRAGSLPVSEIYSFLCQHFPYFENAPSGWK 456
                ||....:....:|..||.|||:.||.:|::.|:...:.:|.||.::..:|.||.:|...|:
Frog   182 ----LQPMEDIDYKTNPHVKPPYSYATLICMAMQASKKTKITLSAIYKWITDNFCYFRHADPTWQ 242

  Fly   457 NSVRHNLSLNKCFEKIERPATNGNQRKGCRWAMNPDRINKMDEEVQKWSRKDPAAIRGAMVYPQH 521
            ||:||||||||||.|:  |.......||..|.::|...:::.....|..|..|..|..|....|.
Frog   243 NSIRHNLSLNKCFIKV--PREKDEPGKGGFWKIDPQYADRLMNGAMKKRRLPPVQIHPAFASAQA 305

  Fly   522 LESLERGEMKHGSADSDVELDSQS-----EIEES-----------------SDLEEHEFEDTM-- 562
            ..|   |....|| ...:.::|:|     |.||:                 ||.:.|:.:..:
Frog   306 AAS---GNSNRGS-PWQLSVNSESHQLLKEFEEATGEQGWNALGEHGWNAISDGKSHKRKQPLPK 366

  Fly   563 ---------VDAMLVEEEDEE---EDGDDDEQIINDFDAEDERHANGNQANNLPINHPL------ 609
                     ...||.:||..|   ..||.|.::|  ||: .....|.:...:|.:..||
Frog   367 RMFKAPRLSSSPMLCQEEQTELGSLKGDFDWEVI--FDS-SMNGVNFSAFEDLEVTPPLSPVTRS 428

  Fly   610 ------------------LG------QKSNDFDIEVGDLYDAIDI-----EDDKESVRRIISNDQ 645
                              ||      |.|.|||    :.:.|...     |:::.......:|.:
Frog   429 VDLTVHGKHIDCPQQWYPLGQDQAVVQNSLDFD----ETFLATSFLQHPWEENRNDYLSNSANIE 489

  Fly   646 HIIELN---PADLN 656
            .:.:||   ||:||
Frog   490 QLFDLNEEFPAELN 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jumu	NP_524302.1	Forkhead	411..499	CDD:278670	35/87 (40%)
foxj1	XP_012827170.1	Forkhead	197..283	CDD:278670	35/87 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920