DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment jumu and FoxK

DIOPT Version :9

Sequence 1:	NP_524302.1	Gene:	jumu / 41265	FlyBaseID:	FBgn0015396	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster

Alignment Length:	749	Identity:	158/749 - (21%)
Similarity:	267/749 - (35%)	Gaps:	246/749 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 VGSSSSDLTSSLDQTLEAISAINNNQSNGNSSQSASYNANANFLT-SSGLHASPT---------- 104
            :.::::..|::|..|....|:.||:.||.|:|.::|:|.|.|.:| .:.|:..||
  Fly     1 MAATTTTTTTTLATTTGNSSSTNNSSSNNNNSIASSHNNNNNIVTVHTVLNNPPTNTAGGGVADA 65

  Fly   105 -----AKWM-----GSSA------NFWSNSDYYADLGACVNPISVMPLINSTSAGMFSPKKNKTA 153
                 ||.|     |::|      |.::||...                |:.||...:...|.:|
  Fly    66 ATVAIAKDMLQLHHGAAAAATAALNNYNNSSNN----------------NNNSADQLTGNSNNSA 114

  Fly   154 SSTQGRSGAVPSSPSAERDQHKSHLTFSPAQMKVSA----GSMRRDQVMAHIPKQISVVTGTGTT 214
            :.....|....||.|:....:.::.:.:.|....|:    |.:|.:|.:..|...::|:....:|
  Fly   115 NHPPATSSTTNSSSSSTTSANTNNPSANAASTLTSSSPPYGELRFNQEVLPITDAVTVIGRNSST 179

  Fly   215 APA--TMATNSV--------------------------------LQRRNSSAVDAVR-------K 238
            :..  .:|.|::                                |||||   ||.:|       :
  Fly   180 SLVHFNVAENNLVSRKHFQVLYDVELRAFFVQCLSKNGIFVDDFLQRRN---VDPLRLPQRCYFR 241

  Fly   239 DLVTELRKAQSSPVPNSLEELGKGKGSTLLNASVGATNTIKLAPGIGGLTFANSAAY-------- 295
            ...||:|....|.||.:..:...|...:|:   ||         |.||:  |...|:
  Fly   242 FPSTEIRIEFESYVPATSSDAIDGHSPSLV---VG---------GGGGV--AGGGAHVIITPLPR 292

  Fly   296 -----QKL----KQTSLVKSPGGISPGAGSNMGLKREDSNKRGLQASTTPKSIASAANSPHHQM- 350
                 |:|    :|..|.:......|.| .::.|:::...:   |.:..|     ..::|||.:
  Fly   293 DELHQQQLHHHQQQPHLQQQQHPHHPPA-HHLPLQQQQQQQ---QPAHHP-----LPHTPHHPLH 348

  Fly   351 -----QSNYSLGS-----------------------------PSSLSSSSASSPLGNVS------ 375
                 |.....||                             |.....|...||.|.:|
  Fly   349 HTALHQQQQRSGSIVVAPPAGAAAHLIAGDGPGIYSPLKISIPKKEQKSPYLSPTGTISAANSCP 413

  Fly   376 -------------NLVNIANNNTSGAGSGLVKPLQQKVKLPPVGS--PFPKPAYSYSCLIALALK 425
                         |..|..||||           |...:.|...|  ...||.|||:.||..|:.
  Fly   414 ASPRQGFIQNQPNNYNNYGNNNT-----------QDLFQTPSTASYNHNEKPPYSYAQLIVQAIS 467

  Fly   426 NSRAGSLPVSEIYSFLCQHFPYF-ENAPSGWKNSVRHNLSLNKCFEKIERPATNGNQRKGCRWAM 489
            .:....|.:|.||||:.:|:||: :....||:||:|||||||:.|.|:.|  :.....||..|.:
  Fly   468 AAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSLNRYFIKVAR--SQDEPGKGSFWRI 530

  Fly   490 NPDRINKMDEEVQKWSR-------KDPAAI-RGAMVYPQHLESLERG-----------------E 529
            :||...|:.:...|..|       :.|..: |.|.|.|.|:::....                 .
  Fly   531 DPDSGAKLIDHSYKKRRQRSSQGFRPPYGMPRSAPVSPSHMDNSRESSPLQDIVLQSAPGSPGMS 595

  Fly   530 MKHGSADSDVELDSQSEIEESSDLEEHEFEDTMVDAMLVEEEDEEEDGDDDEQIINDFD--AEDE 592
            ::..:||.::..:||:..::....::.:.:.|:      .....:........:.|...  |..:
  Fly   596 LEQRAADPEIIYNSQNAHQQQQQQQQQQQQQTL------SNNSNQYSSGSPYYVTNQSSGVATPQ 654

  Fly   593 RHANGNQANN------------LPINHPLLGQKS 614
            .|..|:.|:.            |..||.:.|..|
  Fly   655 THVEGSAASGGGGGGGVGALLALKRNHVMGGGAS 688

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jumu	NP_524302.1	Forkhead	411..499	CDD:278670	37/88 (42%)
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017	15/85 (18%)
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	37/88 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445536
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.750