Protein Alignment jumu and FOXN2

DIOPT Version :10

• Sequence 1: NP_524302.1
• Gene: jumu / 41265
• FlyBaseID: FBgn0015396
• Length: 719
• Species: Drosophila melanogaster
• Sequence 2: NP_002149.2
• Gene: FOXN2 / 3344
• HGNCID: 5281
• Length: 431
• Species: Homo sapiens
• Alignment Length: 402
• Identity: 107/402 - (26%)
• Similarity: 173/402 - (43%)
• Gaps: 101/402 - (25%)

  Fly   354 YSLGS---------PSS--LSSSSASSPLGNVSNL---VNIANNNTSGA-GSGLVKPLQ--QKVK 401
            |.:||         |.:  :.|.||...|.|::.|   .|:..|.:.|: |..:|.||.  :...
Human    28 YKMGSLPEAVDAARPKATLVDSESADDELTNLNWLHESTNLLTNFSLGSEGLPIVSPLYDIEGDD 92

  Fly   402 LPPVG----------SPFPKPAYSYSCLIALALKNSRAGSLPVSEIYSFLCQHFPYFENAPSGWK 456
            :|..|          |...||.||:|.||.:|:::|....|||.||||::..|||||..||:|||
Human    93 VPSFGPACYQNPEKKSATSKPPYSFSLLIYMAIEHSPNKCLPVKEIYSWILDHFPYFATAPTGWK 157

  Fly   457 NSVRHNLSLNKCFEKIERP--ATNGNQRKGCRWAMNPDRINKMDEEVQKWSRKDPAAIRGAMVYP 519
            |||||||||||||:|:||.  ..||   ||..|.::|:....:.:.::|......::..|:: .|
Human   158 NSVRHNLSLNKCFQKVERSHGKVNG---KGSLWCVDPEYKPNLIQALKKQPFSSASSQNGSL-SP 218

  Fly   520 QHLESLERGEMKHGSADSDVELDSQSEIEESSDLEEHEFEDTMVDAMLVEEEDEEEDGDDDEQII 584
            .:|.|:.:........:||::..:                     ||::.....|:...:.|:.:
Human   219 HYLSSVIKQNQVRNLKESDIDAAA---------------------AMMLLNTSIEQGILECEKPL 262

  Fly   585 NDFDAEDERHANGNQANNLPINHPLLGQKSNDFDIEVGDLYDAIDIEDD---------------K 634
            ....|..::.:.||     ..:||...:..     |...|..:||.::|               :
Human   263 PLKTALQKKRSYGN-----AFHHPSAVRLQ-----ESDSLATSIDPKEDHNYSASSMAAQRCASR 317

  Fly   635 ESVRRIISNDQHIIELNPADLN-ATDG-------------YNQQPALKRARVDINYAIGPAGELE 685
            .||..:.|.|: :.|..|.:.: .:||             |...|.     .|..||..|..::.
Human   318 SSVSSLSSVDE-VYEFIPKNSHVGSDGSEGFHSEEDTDVDYEDDPL-----GDSGYASQPCAKIS 376

  Fly   686 Q--QYGQKVKVQ 695
            :  |.|:|::.|
Human   377 EKGQSGKKMRKQ 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jumu	NP_524302.1	COG5025	<254..>523	CDD:227358	71/197 (36%)
		FH_FOXN1-like	411..491	CDD:410804	47/81 (58%)
FOXN2	NP_002149.2	FH_FOXN2	111..192	CDD:410832	47/83 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..387		7/22 (32%)