DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jumu and Foxk2

DIOPT Version :9

Sequence 1:	NP_524302.1	Gene:	jumu / 41265	FlyBaseID:	FBgn0015396	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	XP_006247952.1	Gene:	Foxk2 / 303753	RGDID:	1305408	Length:	650	Species:	Rattus norvegicus

Alignment Length:	383	Identity:	91/383 - (23%)
Similarity:	147/383 - (38%)	Gaps:	106/383 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   259 LGKGKGSTLLNASVGATNTIK------LAPGIGGLTFANSAAYQKLKQTSLVKSPGGISPGAGSN 317
            :|:......::.|:|.::.|.      ..|..||    :|||         ...|....|.||.:
  Rat    50 IGRNSSQGSVDVSMGHSSFISRRHLEIFTPPGGG----HSAA---------APEPAQPRPDAGGD 101

  Fly   318 MGLKREDSN---------KRG---LQ---------ASTTPKSIASAANSPHHQMQ---------- 351
            ..|:....|         :||   ||         .||..|...:|.:|...:.|
  Rat   102 FYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSSEKREKQEAPESPVKPV 166

  Fly   352 ----SNYSLGSPSSLSS--SSASSPLGNVSNLVNIANNNTSGAGS-----GLVKP---------L 396
                |..::..|.:::.  |...||.|.:| ..|...::..||||     |.|.|         .
  Rat   167 QPHISPLTINIPDTMAHLISPLPSPTGTIS-AANSCPSSPRGAGSSGYKMGRVIPSDLNLMADNS 230

  Fly   397 QQKVKLPPVGSPFP----KPAYSYSCLIALALKNSRAGSLPVSEIYSFLCQHFPYFENAPSGWKN 457
            |.:.:....|...|    ||.|||:.||..|:..:....|.::.||:.:.:::||:..|..||:|
  Rat   231 QPENEKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQN 295

  Fly   458 SVRHNLSLNKCFEKIERPATNGNQRKGCRWAMNPDRINKMDEEVQKWSRK----------DPAAI 512
            |:|||||||:.|.|:  |.:.....||..|.::|...:|:.|:..:..|.          .|.:.
  Rat   296 SIRHNLSLNRYFIKV--PRSQEEPGKGSFWRIDPASESKLVEQAFRKRRPRGVPCFRTPLGPLSS 358

  Fly   513 RGAMVYPQHL-------------ESLERG------EMKHGSADSDVELDSQSEIEESS 551
            |.|...|.|.             |||.|.      |.:.|::...:.:..::...:|:
  Rat   359 RSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGASQPKLAVIQEARFAQSA 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jumu	NP_524302.1	Forkhead	411..499	CDD:278670	33/87 (38%)
Foxk2	XP_006247952.1	FHA	41..145	CDD:238017	23/107 (21%)
Foxk2	XP_006247952.1	Forkhead	249..335	CDD:278670	33/87 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820