DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment jumu and Foxn4

DIOPT Version :9

Sequence 1:	NP_524302.1	Gene:	jumu / 41265	FlyBaseID:	FBgn0015396	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_001376188.1	Gene:	Foxn4 / 288736	RGDID:	1306389	Length:	572	Species:	Rattus norvegicus

Alignment Length:	533	Identity:	158/533 - (29%)
Similarity:	228/533 - (42%)	Gaps:	107/533 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   143 GMFSPKKNKTASSTQGRSGAVPSSPSAERDQHKSHLTFSPAQ----------MKVSAGSMRRDQV 197
            |.....|.|..||..||..:.....||.....:|....||.|          ::.....|.|...
  Rat     5 GQLQRGKFKNGSSCDGRPNSRQQGASAREYPCRSAARPSPTQDPLQEMIESDIQSKMSGMIRSSG 69

  Fly   198 MAH--IPKQISVVTGTG-TTAPATMATNSVLQRRNSSAVDAVRKDLVTELRKAQSSPVPNSLEEL 259
            .:|  .|::...:...| ...|..:.:.|.|     :|||..|...:...|....||   |:...
  Rat    70 HSHHRSPQEYRFLPPAGDDDLPGDLQSLSWL-----TAVDVPRLQQMASGRIDLGSP---SVPHP 126

  Fly   260 GKGKGSTLLNASVGA-------TNTIKLAPGIGGLTFANS--AAYQKLKQTSLVKSPGGISPGAG 315
            ..|..:.:.:..|||       :.|..:..|:.||:...|  |:.:::.|..:         |..
  Rat   127 HPGAMAGVADPHVGAAPRPMLRSQTAMVPRGMLGLSPIGSYRASAEQMNQFPV---------GGQ 182

  Fly   316 SNMGLKREDSNKRGLQASTTPKSIASAANSPHHQMQSNYSLGS----PSSLSSSSASS----PLG 372
            |:.||:.            .|:     ..||..|:|.....||    |:||..|..::    |..
  Rat   183 SSSGLQE------------MPQ-----LYSPATQIQFPLPSGSQQCPPTSLYGSPFAARPPYPQA 230

  Fly   373 NVSNLVNIANNNTSGAGSGLVKPLQQKVKLPPVGSP--FPKPAYSYSCLIALALKNSRAGSLPVS 435
            :|:                        |..|....|  :|||.||||||||:|||:|:.||||||
  Rat   231 HVT------------------------VHSPQEAHPKHYPKPIYSYSCLIAMALKSSKTGSLPVS 271

  Fly   436 EIYSFLCQHFPYFENAPSGWKNSVRHNLSLNKCFEKIE-RPATNGNQRKGCRWAMNPDRINKMDE 499
            |||||:.:|||||:.||.||||||||||||||||||:| :|  :|:.||||.||:|..||:|::|
  Rat   272 EIYSFMKEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVETKP--SGSSRKGCLWALNLARIDKVEE 334

  Fly   500 EVQKWSRKDPAAIRGAMVYPQHLESL--ERGEM-----KHGSADSDVELDSQSEIEESSDLEEHE 557
            |:.||.|||.|||..:|..|:.|:.|  :|.|.     |.|..:..|...:.:.....|.|...:
  Rat   335 EMHKWKRKDLAAIHRSMANPEELDKLISDRPESCRRPGKQGEPEVPVLTRATTVAMTHSCLAISQ 399

  Fly   558 FEDTMVDAMLVEEEDEEEDGDDDEQIINDFDAEDER---HANGNQANNLPINHPLLGQKSNDF-- 617
            .....:..:.::.............:..|..|..:.   ||..|.:.. |:..|.:|:...||
  Rat   400 LPPKPLMTLSLQSVPLHHQVQPQAHLAPDSPAPAQTPPLHALPNLSPG-PLPQPAVGRVPGDFLN 463

  Fly   618 -DIEVGDLYDAID 629
             ..:.....||:|
  Rat   464 ISTDTNTEVDALD 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jumu	NP_524302.1	Forkhead	411..499	CDD:278670	63/88 (72%)
Foxn4	NP_001376188.1	COG5025	<143..>357	CDD:227358	103/265 (39%)
Foxn4	NP_001376188.1	FH_FOX	242..347	CDD:412138	73/106 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	135	1.000	Domainoid score	I4843
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007398
OrthoInspector	1	1.000	-	-		otm45714
orthoMCL	1	0.900	-	-		OOG6_107576
Panther	1	1.100	-	-	LDO	PTHR13962
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.000