DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jumu and Foxj3

DIOPT Version :9

Sequence 1:	NP_524302.1	Gene:	jumu / 41265	FlyBaseID:	FBgn0015396	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_001344106.1	Gene:	Foxj3 / 230700	MGIID:	2443432	Length:	623	Species:	Mus musculus

Alignment Length:	328	Identity:	85/328 - (25%)
Similarity:	137/328 - (41%)	Gaps:	71/328 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   354 YSLGSPSSLS---SSSASSPLGNVSNLVNI----------ANNNTSGAG----SGLVKPL----Q 397
            |....||..|   :|...|.|.::..|..:          |..|..|.|    :.|:.|.    |
Mouse     4 YGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTGISKKNALLDPNTTLDQ 68

  Fly   398 QKVKLPPVGSPFPKPAYSYSCLIALALKNSRAGSLPVSEIYSFLCQHFPYFENAPSGWKNSVRHN 462
            ::|:....|    ||.|||:.||..|:.:|....:.:||||.::|.:|||:..|.||||||:|||
Mouse    69 EEVQQHKDG----KPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHN 129

  Fly   463 LSLNKCFEKIERPATNGNQRKGCRWAM--NPDRINKMDEEVQKWSRKDPAAIRGAMVYPQHLESL 525
            |||||||.|:  |.:..:..||..||:  ||    |.|....:..::..:..|.:..|....:||
Mouse   130 LSLNKCFLKV--PRSKDDPGKGSYWAIDTNP----KEDTLPTRPKKRARSVERASTPYSIDSDSL 188

  Fly   526 ERGEMKHGSADSDVELDSQSEIEESSDLEEHEFEDTMVDAMLVEEEDEEEDGDDD--EQIINDFD 588
            ....:..|||...:.:::.:.            :.|:.:|        ::||.|.  ..:.|...
Mouse   189 GMECIISGSASPTLAINTVTN------------KVTLYNA--------DQDGSDSPRSSLNNSLS 233

  Fly   589 AEDERHANGNQANNL-----------PINHPLLGQKSNDFDIEVGD-----LYDAIDIEDDKESV 637
            .:.....|.|...::           |::.||..|:.......:.:     |:...:.||...|.
Mouse   234 DQSLASVNLNSVGSVHSYTPVTNHPEPVSQPLTPQQQQQPQYNLPEREKQLLFTEYNFEDLSASF 298

  Fly   638 RRI 640
            |.:
Mouse   299 RSL 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jumu	NP_524302.1	Forkhead	411..499	CDD:278670	43/89 (48%)
Foxj3	NP_001344106.1	COG5025	<54..347	CDD:227358	73/278 (26%)
		Forkhead	78..155	CDD:365978	40/78 (51%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	143..178		9/38 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	248..275		4/26 (15%)
		PAT1	<311..>434	CDD:370676
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	316..451
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910