DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jumu and FOXI1

DIOPT Version :9

Sequence 1:	NP_524302.1	Gene:	jumu / 41265	FlyBaseID:	FBgn0015396	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_036320.2	Gene:	FOXI1 / 2299	HGNCID:	3815	Length:	378	Species:	Homo sapiens

Alignment Length:	261	Identity:	70/261 - (26%)
Similarity:	109/261 - (41%)	Gaps:	63/261 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   391 GLVKPLQQKVKLPPV----GS-----PFP---------KPAYSYSCLIALALKNSRAGSLPVSEI 437
            |:.:||     ||.|    ||     |.|         :|.||||.|||:|:..:....|.:|:|
Human    90 GVQRPL-----LPSVSGLGGSDLGWLPIPSQEELMKLVRPPYSYSALIAMAIHGAPDKRLTLSQI 149

  Fly   438 YSFLCQHFPYFENAPSGWKNSVRHNLSLNKCFEKIERPATNGNQRKGCRWAMNPDRINKMDEE-- 500
            |.::..:||::..:.:||:||:|||||||.||:|:  |....:..||..|.::|: ..||.:.
Human   150 YQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKV--PRDEDDPGKGNYWTLDPN-CEKMFDNGN 211

  Fly   501 -VQKWSRKDPAAIRGAMVYPQHLESLERGEMKHGSADSDVELDSQSEIEESSDLEEHEFEDTMVD 564
             .:|..||...:...|.:      :||:.|       |.:.:||....|....|     :.....
Human   212 FRRKRKRKSDVSSSTASL------ALEKTE-------SSLPVDSPKTTEPQDIL-----DGASPG 258

  Fly   565 AMLVEEEDEEEDGDDDEQIINDFDAEDERHANGNQANNLPINHPLL------------GQKSNDF 617
            ......|............:|.|.:....:.:|..    |.:|||:            ||.|..|
Human   259 GTTSSPEKRPSPPPSGAPCLNSFLSSMTAYVSGGS----PTSHPLVTPGLSPEPSDKTGQNSLTF 319

  Fly   618 D 618
            :
Human   320 N 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jumu	NP_524302.1	Forkhead	411..499	CDD:278670	36/87 (41%)
FOXI1	NP_036320.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		FH	123..211	CDD:214627	36/90 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	208..278		13/87 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820